Amla (Emblica officinalis): Role in health management via controlling various biological activities

Almatroodi, Saleh A.; Alsahli, Mohammed A; Almatroudi, Ahmad; Dev, Kapil; Rafat, Sahar; Verma, Amit Kumar; Rahmani, Arshad Husain

doi:10.1016/j.genrep.2020.100820

Cited by 12 publications

(9 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, Rizwan et al [33] have reported that Phyllanthus emblica fruit extract is an inexpensive way to treat subclinical mastitis, and it can also be used to substitute antibiotic therapy to produce antibiotic residue-free milk. Almatroodi et al [34] reviewed that amla fruit can be used as a natural feed additive in health management and this has been proven through its antioxidant, anti-inflammatory, hepatoprotective, gastroprotective, anti-diabetic, anti-microbial, neuro-protective, cardioprotective, and immunomodulatory activity [34].…”

Section: Introductionmentioning

confidence: 99%

Fresh Phyllanthus emblica (Amla) Fruit Supplementation Enhances Milk Fatty Acid Profiles and the Antioxidant Capacities of Milk and Blood in Dairy Cows

et al. 2022

View full text Add to dashboard Cite

The objective of this study was to investigate the effect of a diet supplemented with fresh amla fruit as a natural feed additive on blood metabolic parameters, milk antioxidant capacity, and milk fatty acid (FA) proportions in lactating dairy cows. Eight ruminally cannulated mid-lactation dairy cows were used in a repeated crossover design. The first group of four cows received total mixed ration (TMR) feed without fresh amla fruit (control group). The remaining four cows sequentially supplemented fresh amla fruit (FAF) at three levels (200, 400, then 600 g/d) (treatment group) at 14-day intervals. In second period, control and treatment groups were exchanged. The first ten days were adjusted to diet adaptation for each sub-period, and the last four days for sampling milk and blood. A total of 514 metabolites were detected from FAF using UPLC-ESI-MS/MS. The five main metabolites in FAF were phenolic acids (22%), flavonoids (20%), lipids (20%), amino acids and derivatives (9%), and tannins (7%). Amla fruit supplementation reduced total saturated fatty acid and the omega-6/omega-3 ratio at 200 or 400 g/d FAF dose compared to controls. In addition, amla fruit increased unsaturated FA, such as C20:5 (Eicosapentaenoic acid, EPA) and C22:6 (docosahexaenoic acid, DHA), and branched-chain FA in a dose-dependent manner at 200 or 400 g/d compared to controls. In addition, amla fruit increased the antioxidant capacity biomarkers in the blood, such as superoxide dismutase (SOD) and albumin; this confirms that amla fruit is an excellent antioxidant, inhibiting reactive oxygen species’ (ROS) metabolism, and can thereby protect cells from oxidative stress. Moreover, the most remarkable improvement of ferric reducing-antioxidant power (FRAP) and total antioxidant capacity (TAC) in milk was recorded at 400 g/d FAF doses compared to controls. Therefore, fresh amla fruit doses for lactating cows at 400 g/d on an as-fed basis can be used as an alternative additive feed in dairy cow diets to improve antioxidant capacity, protein efficiency, butter quality, and to produce more desirable milk fatty acid profiles for human consumption.

show abstract

Section: Introductionmentioning

confidence: 99%

Fresh Phyllanthus emblica (Amla) Fruit Supplementation Enhances Milk Fatty Acid Profiles and the Antioxidant Capacities of Milk and Blood in Dairy Cows

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Since ancient times, amla has been used in management of various diseases, and laboratory studies based on in vivo and in vitro investigations have confirmed its role. Amla has been used as a traditional medicine to cure various diseases like constipation, diabetes, hyperlipidemia, CNS disorders, asthma, and ophthalmic diseases (Almatroodi et al, 2020). Potential of amla fruit/pulp extract against management of various diseases has been proved through various in vivo and in vitro studies (Table 3).…”

Section: Therapeutic Properties Of Amlamentioning

confidence: 99%

“…Substantial antiproliferative activity has also been reported for amla extract (Khan et al, 2019). Amla extract can be used to treat acute gastric ulcers, owing to its effect on increased secretion of gastric mucus and hexamine, and preventing the stomach wall from lesions (Almatroodi et al, 2020). Substantial antitumor activity of Emblica officinalis was observed in in vitro study against various cancer cell lines, A549 (lung), HepG2 (Hepatocytes), MDB‐MB‐231 (breast, triple negative), HeLa (cervical), SK‐OV3 (ovarian), and SW620 (colorectal), and in vivo study of mice skin tumor induced by DMBA/TPL (Ngamkitidechakul et al, 2010).…”

Section: Therapeutic Properties Of Amlamentioning

confidence: 99%

Insight about the biochemical composition, postharvest processing, therapeutic potential of Indian gooseberry (amla), and its utilization in development of functional foods—A comprehensive review

Muzaffar

Sofi

Makroo

et al. 2022

Journal of Food Biochemistry

View full text Add to dashboard Cite

Indian gooseberry/Amla (Emblica officinalis Gaertn. syn. Phyllanthus emblica L) has an amazing nutritional profile and is a reservoir of biologically active compounds which have potential health benefits and are regarded as a remedy for lethal diseases. The unique features of amla, conferred by their bioactive components, have extended future prospects about their usage for useful effects on human nutrition and health globally. With the rapidly growing popularity of this unique therapeutic fruit, it is important to have comprehensive knowledge of this fruit. The current review article presents the nutritional profile, bioactive components, antioxidant and antimicrobial properties, and postharvest processing of amla fruit. Moreover, studies related to therapeutic properties of amla and its utilization in development of functional foods have been presented in this review. E. officinalis is a promising source of bioactive compounds which showed varied potential in the management of a number of human ailments which has been proven through various studies. Therefore, amla should be taken in the regular diet, thereby utilizing its potential health benefits. Practical applicationsAmla (Indian gooseberry), as source of natural bioactive compounds, has a great potential application in improving the status of human nutrition and health. The utilization of amla extract has various biological effects, like antimicrobial, antioxidant, gastroprotective, anticancer, hepatoprotective, cardioprotective, radioprotective, anti-inflammatory, antidiabetic, neuroprotective, and immunomodulatory effect, owing to its bioactive components. The use of amla extract has recently increased in food, pharmaceutical, and cosmetic products to replace synthetic antioxidants which have inherent harmful health effects. The review report will provide information on bioactive components, therapeutic properties, utilization of amla in the development of future functional foods, and postharvest processing of amla, which will provide critical information to researchers all over the world.

show abstract

“…They are known for high amount of ascorbic acid (500–1,500 mg/100 g) content (Chakraborty, Ghag, Bhalerao, & Gokhale, 2020; Mehta, Singh, Singh, Prabhakar, & Kumar, 2021). It is a low‐cost and essential fruit in ayurvedic and unani system, and it possesses many therapeutic effects (Almatroodi et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Prediction of mass‐based process designing parameters of amla fruit using different modeling techniques

Tomar

Pradhan

2022

J Food Process Engineering

View full text Add to dashboard Cite

The machine designing parameters such as size, volume, criteria projected area are important for quality evaluation at the time of packaging, grading, and sorting of fruits. All these designing parameters also depend on mass of the fruit sample. So, the correlation between mass and designing parameters could be useful for automation of the process industry. The research was inducted to predict the dimension, projected area, and volume of fruit as a function of fruit mass. Prediction modeling was done using different models, that is, mathematical model (MM), artificial neural network (ANN), and support vector regression (SVR). The mathematical model (linear, quadratic, and power) showed better prediction results than SVR modeling. In addition, the best results were achieved by neural network‐based prediction modeling. It showed the highest correlation coefficient of .884, .986, .992, .999 and the lowest error of 0.570, 0.241, 8.080, 0.059 for height, diameter, projected area, and volume, respectively. It is observed that the physical properties of fruit can be predicted using ANN‐based modeling which could be useful in automation and efficient designing of post‐harvest equipment. Practical Application The machine designing parameters are the essential and fundamental parameters for designing of grading, sorting, packaging, and handling equipments of various horticultural products including amla. Fruits and vegetables are non‐uniform in size and shape. So, minor changes in shape and size of fruits could decrease the efficiency of various processes and its equipment. The design parameters of fruits and vegetables are dependent on the mass of samples. So, accurate knowledge of mass and design parameters could help in designing the automatic grading system. Different models can be used to predict various designing parameter of amla or similar fruits. By using various models, fruit can be separated more accurately based on minor changes in shape and size rather than its mass. The ANN‐based prediction will be beneficial for the automation of the fruits grading system at an industrial scale.

show abstract

Amla (Emblica officinalis): Role in health management via controlling various biological activities

Cited by 12 publications

References 51 publications

Fresh Phyllanthus emblica (Amla) Fruit Supplementation Enhances Milk Fatty Acid Profiles and the Antioxidant Capacities of Milk and Blood in Dairy Cows

Fresh Phyllanthus emblica (Amla) Fruit Supplementation Enhances Milk Fatty Acid Profiles and the Antioxidant Capacities of Milk and Blood in Dairy Cows

Insight about the biochemical composition, postharvest processing, therapeutic potential of Indian gooseberry (amla), and its utilization in development of functional foods—A comprehensive review

Prediction of mass‐based process designing parameters of amla fruit using different modeling techniques

Contact Info

Product

Resources

About