Abstract:Traumatic brain injury (TBI) is a significant global health issue due to its high morbidity and mortality, as well as its adverse outcomes. The resulting excessive healthcare and economic burden make it urgent to find effective drugs for TBI. Aminophylline (AMP), a classical drug widely used in the treatment of cardiovascular diseases and bronchiectasis, has recently been found to play an important role in protecting neurons in hypoxia brain injury by a variety of mechanisms. However, its therapeutic effect on… Show more
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