Amino acid catalyzed thio-Michael addition reactions

Preparation of HMX/TATB Composite Particles Using a Mechanochemical Approach

“…3‐(Ethylthio)‐1‐(4‐methoxyphenyl)‐3‐phenylpropan‐1‐one (3 m) :15a 134.1 mg, 89 % yield; white solid; m.p. 69.5–71.4 °C.…”

Arginine‐Catalyzed Henry Reaction of α‐Keto Amides with Nitromethane on Water

“…Taking advantage of cheap and nontoxic properties, amino acids are ideal catalysts in catalytic organic synthesis. For example, amino acids and their derivatives were successfully employed in the aldol reactions, [9] Michael reactions [10] and many other transformations. [11] However, amino acids-catalyzed reactions are much less carried out in an aqueous system.…”

Microwave-assisted solvent-free synthesis of α,α′-bis(substituted benzylidine)cycloalkanones catalyzed by /ZrO2and B2O3/ZrO2

“…The use of ionic liquids (25), acidic alumina (26), CTAB/NaOH (27), copper(II) trifluoroacetate (28), lanthanide amides (29), sulphonic acid (30), silica sulfuric acid (31), K 2 CO 3 /PEG (32), and TCT (33) has also been proven effective for the synthesis of title compounds. Several recent literature have reported the use of molecular iodine (4), NaOAc (34), ZrCl 4 (35) as benign catalysts for the synthesis of bis-benzylidene cycloalkanones. However, in most cases the yields are good at high temperatures and some of the reagents require longer reaction times with tedious purification procedures utilizing large quantities of volatile organic solvents.…”