Amenorrhea as a Side Effect of Low Dose Aripiprazole: An Adolescent Case

Abstract

Amenorrhea, oligomenorrhea, galactorrhoea, gynecomastia, infertility, and sexual dysfunction may arise as a consequence of hyperprolactinemia. Hyperprolactinemia is one of major side effects of treatment with antipsychotics, but aripiprazole is known as a dopamine stabilizer antipsychotic which can be used to improve hyperprolactinemia. In this report, it was described that an adolescent patient experienced amenorrhea after adding very low dose aripiprazole to ongoing fluoxetine treatment regime for major depressive disorder. Additionally, this case showed that the patient recovered from the amenorrhea with replacement of aripiprazole with quetiapine.

Amenorrhea as a Side Effect of Low Dose Aripiprazole: An Adolescent Case

“…Guler et al 1). have recently reported an interesting case of amenorrhea in the setting of an adolescent girl with major depressive disorder (MDD) being treated with fluoxetine (FLUX) 40 mg and aripiprazole (ARIP) 5 mg/day.…”