Amenorrhea and elevated βhuman chorionic gonadotropin of unknown origin: An unexpected location of choriocarcinoma

Abdallah, I. Ben; Mlika, Mona; Berrazega, Y.; Mejri, Nesrine; Rachdi, Haifa; Benna, Houda El; Daoud, Nouha; Laabidi, S.; Mezni, Faouzi El; Boussen, Hamouda

doi:10.1016/j.gore.2021.100746

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Choriocarcinoma is a highly invasive malignant tumor originating from the trophoblast epithelium of pregnancy. In rare cases, choriocarcinoma can originate in the external genital region, predominantly in midline structures such as the retroperitoneum, mediastinum, and pineal gland ( 1 , 2 ). Tumor tissue is composed of cytotrophoblasts, syncytiotrophoblasts, and variable intermediate trophoblasts that secrete β-human chorionic gonadotropin (β-hCG) ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

The tumor or inflammation? a case report on primary pulmonary choriocarcinoma

Wang

Zhang

et al. 2023

Front. Oncol.

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Choriocarcinoma is a rare malignant germ cell neoplasm with high invasiveness, the majority of which are pregnancy-related, and the female genital tract is the most prevalent site of the disease. Although early-stage choriocarcinoma typically metastasizes to the lungs, primary pulmonary choriocarcinoma is extremely rare. Primary pulmonary choriocarcinoma is difficult to diagnose, and it progresses rapidly. Combined with the difficulty of treatment, the prognosis of patients is generally poor. In this article, we retrospectively analyzed a case of female primary pulmonary choriocarcinoma, combined with a review of literature, to understand and describe the diagnostic and treatment progress of PPC.

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Section: Introductionmentioning

confidence: 99%