Ameloblastomas sólidos: estudo retrospectivo clínico e histopatológico em 54 casos

Abstract

Recent ly, the World Health Organization (WHO) excluded the desmoplastic pattern from the histopathological spectrum of solid ameloblastomas and classified it as a distinct variant, named desmoplastic ameloblastoma. Aim: To perform a retrospective analysis of the clinicopathologic aspects in a case series of solid ameloblastomas. Study design: Crosssectional cohort study. Materials and methods: Data regarding age, gender, location and clinical characteristics were retrieved from patient records. Histological sections were evaluated regarding existing histological patterns and the predominant histological pattern. Cases were classified according to the study of Waldron and El-Mofty (1987) and the WHO classification of 2005. Results: A total of 54 cases were identified, with similar gender distribution and a mean age of 38.3 years. Fifty three cases (98.1%) affected the mandible. Forty nine cases (90.8%) were classified as solid ameloblastomas, 3 (5.6%) as desmoplastic ameloblastomas, and 2 (3.7%) as hybrid lesions. The most frequent histological patterns in solid ameloblastomas were follicular (77.6%), acanthomatous (69.4%), and plexiform (65.3%). Focal areas of desmoplastic ameloblastomas were identified in 11 solid ameloblastomas (22.4%). Conclusion: Despite its characterization as a distinct variant, our results revealed that focal areas of desmoplastic ameloblastomas can be observed with some frequency in conventional ameloblastomas.

Aggressive Plexiform Ameloblastoma in a Young Girl: A Case Report

“…4, Issue 4, April, 2017 population (6).Histopathologically ameloblastoma is classified into 6 subtypes :a)follicular b)plexiform c)acanthomatous d)desmoplastic e)granular and f)basal cell type (7).According to 2005 WHO classification Ameloblastoma is classified under3 major category as solid, desmoplastic and hybrid. Solid Ameloblsatopma further classified as Follicular, plexiform and acanthomatous (8). Radiologically they may be unilocular or multilocular .Plexiform type of ameloblastoma present less aggressive form (9).…”

Hybrid Ameloblastoma in the Anterior Man-dible

“…It is a rare type of the tumor (1% -4%) [3]- [5] and was first described in detail by Waldron and El-Mofty in 1987 [10]. Takata et al (1999) reviewed 8 cases of this type.…”

“…"Hybrid" ameloblastoma is a rare variant (about 1% -4% of ameloblastomas) [3]- [5] in which typical areas of follicular or plexiform pattern (generally called onventional ameloblastoma) coexist with areas of pronounced stromaldesmoplasia (desmoplastic ameloblastoma). They most often (80%) occur in the mandible.…”

“…They most often (80%) occur in the mandible. Although conventional ameloblastoma has no gender difference in prevalence [1], desmoplastic variant is seen more in men [5]; whereas hybrid ameloblastoma has slight female predilection with M:F ratio 11:16 [6], and mostly in the fourth and fifth decades of life (mean age of 36) [1] [7] [8]. The most prevalent symptom is facial swelling [1]; but as the tumor is locally aggressive, it can destroy surrounding tissues.…”

Maxillary Ameloblastoma: A Rare Case Report

“…5 According to the literature, solid ameloblastoma occurred least frequently in the maxillary bone. 3,6 Based on the recent classification of odontogenic tumors, by World Health Organization (WHO), benign ameloblastomas are recognized in four subtypes: solid/ multicystic, desmoplastic, unicystic and the extraosseous/peripheral types. Solid ameloblastomas affect the mandible preferably, especially the posterior region with a proportion between the gnathic bones of 1:5.…”