Ameloblastic fibro-odontoma: Case report and immunohistochemical profile

Ameloblastic fibro-odontoma with a predominant radiopaque component

“…Despite the considerable size the lesions of AFO may attain, pain and/or paresthesia are unusual symptoms, although tooth displacement may occasionally occur. [ 2 ] Our patient presented with no complaints of pain or parsesthesia despite evidence of downward displacement of the inferior alveolar canal due to the lesion. In addition, our patient also did not exhibit any tooth displacement in relation to 46.…”

“…However, when clinical characteristics of these lesions are analyzed, AFO is more frequent in a younger age group with a mean age of 9.6 years, than AF, which affects individuals with a mean age of 14.8 years, thereby in disagreement to the continuous differentiation hypothesis. [ 2 ] Philipsen et al . suggested the hypothesis of two lines of development for AF, AFD, and AFO.…”

“…The use of carnoy's solution and cryosurgery has also been reported to reduce the chances for recurrence. [ 2 ]…”

“…[ 1 ] While ameloblastomas and odontomas are encountered more frequently, ameloblastic fibro-odontoma (AFO) is rare, accounting for 1%– 3% of all the odontogenic tumors. [ 2 ] AFO was defined as a lesion similar to ameloblastic fibroma (AF), but also showing inductive changes that lead to the formation of both dentine and enamel. [ 3 ] However, AFO is presently defined by the World Health Organization as a neoplasm consisting of odontogenic ectomesenchyme resembling the dental papilla, epithelial strands, and nest resembling dental lamina and enamel organ in conjunction with the presence of dentine and enamel.…”