Ameliorative effects of dietary Vitamin‐C on growth performance and hemato‐biochemical response of sodium fluoride‐intoxicated Amur Carp, Cyprinus carpio haematopterus

Abstract

This study aimed to assess the ameliorative dietary effect of vitamin‐C against sodium fluoride (NaF)‐induced toxicity on growth and haemato‐biochemical parameters in Amur carp. A total of 150 fish (average body weight 169 ± 0.69 g) were randomly distributed into five groups (with three triplicates) including G1 (control); G2 (NaF exposure @100 ppm); G3 (vitamin‐C supplemented diet @100 ppm); G4 (both NaF exposure @100 ppm and vitamin‐C supplemented diet @100 ppm) and G5 (NaF exposure @100 ppm for 60 days and then vitamin‐C supplemented diet @200 ppm for last 30 days). Results revealed that growth and hemato‐biochemical profile was best in G3 in comparison with G1, whereas groups G2, G4 and G5 have shown retarded growth, a decrease in Hb, TEC, PCV, MCV, MCH and MCHC. Serum‐biochemical parameters were found optimum in G3 as compared with G1 and in groups of G2, G4 and G5, total serum protein, albumin, globulin, glucose, and triglyceride levels decreased significantly, whereas creatinine, AST and ALT levels increased significantly. In G4, toxicity was less severe in comparison with G2, whereas in G5, after the dietary supplementary of vitamin‐C, parameters have shown a bend towards the normal values. Thus, it can be concluded that vitamin‐C has ameliorative action against fluoride toxicity in fish.

Combined Effects of Butyl Hydroxytoluene and Vitamin C on the Growth Performance, Blood Biochemistry, and Antioxidative Status of Common Carp (Cyprinus Carpio)

“…The formation of protein in serum is one of the roles of the liver, which means that liver failure causes a low protein synthesis. However, in the current study, the levels of proteins, albumin, and globulin increased by BHT or/and vitamin C. Similar results were seen by Kaur et al (2022), who increased blood protein, albumin, and globulin in Amur carp fed dietary vitamin C. This can be explained by the lack of liver failure and thereby regulated protein, albumin, and globulin secretions. In this context, the reduction of ALT and AST can also be related to the lack of liver damage since a damaged liver led to high secretion of ALT and AST (Vali et al, 2020).…”

“…Further, Wu et al (2022) and Nasar et al (2021) stated that Gibel carp (Carassius gibelio) and grass carp (Ctenopharyngodon idella) fed vitamin C showed improved growth performance. Similar results were seen by Kaur et al (2022), who stated enhanced growth performance in Amur carp (Cyprinus carpio haematopterus) fed dietary vitamin C. Vitamin C has a growth promotion role due to its role in the synthesized collagen involved in tissue formation (Tewary and Patra, 2008). Further, regulated metabolic and physiological functions resulting from vitamin C feeding may explain the enhanced growth performance in common carp (Chen et al, 2015).…”

Effects of Dietary Vitamin C on the Growth Performance, Antioxidant Activity and Disease Resistance of Fish: A Review

“…Ongoing investigations into the application of VC in aquaculture have been prompted by these inquiries into the potential advantages of VC for fish growth, antioxidant activity, and disease resistance (Liu et al, 2021;Kaur et al, 2022). As a result, a comprehensive evaluation is required to consolidate and analyze the numerous information sources.…”