Ameliorative Effects of Aqueous Extract of Colocasia esculenta Leaf Against Lipopolysaccharide-Induced Prefrontal cortex damage in Mice
Jacob Adewale Siyanbade,
Kingsley Afoke Iteire,
Sunday Aderemi Adelakun
et al.
Abstract:Background
The prefrontal-cortex (PFC) occupies about one-third of the total area of the cerebral cortex and it plays crucial role in Cognition and memory. This study evaluated the ameliorative effects of aqueous extract of Colocasia esculenta leaf (AECEL) on lipopolysaccharide-induced Prefrontal-cortex damage.
Methods
42 Swiss male albino mice with weights ranging between 18 − 22g were randomized into six-groups. Group-A consisted of healthy-mice and LPS-induction in groups (B-F) was done by intraperitoneal… Show more
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