Ameliorative effect of ink extract and polysaccharide of Sepia officinalis on hepatotoxicity, renal toxicity and hematological disorders in adult male albino rats treated with cyclophosphamide
Abstract:We aimed to investigate ameliorative effects of the crude extract (SIE) and polysaccharide (SIP) of the ink of Sepia officinalis, on some biochemical and hematological disorders induced by cyclophosphamide (CP). Forty adult male albino Wistar rats were divided into five groups (n= 8 each). In the control group, rats were administered orally with 0.9% isotonic saline solution at a dose (5 ml/kg b.w.). All the other groups were i.p. injected with a single dose of CP (200mg/kg b.w.) only for one time. Then the th… Show more
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