Amelioration of Body Odor After Intracutaneous Axillary Injection of Botulinum Toxin A

Heckmann, Marc; Teichmann, Bianca; Pause, Bettina M.; Plewig, Gerd

doi:10.1001/archderm.139.1.57

Cited by 65 publications

(40 citation statements)

References 23 publications

(28 reference statements)

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“…There was a significant reduction in the pain and sleep time in the BT-A treated group in comparison to the lidocaine and placebo groups (Heckmann et al, 2003). The same results were seen in many case reports (Lee, 2004;Watson and Evans, 1986).…”

Section: Post-herpetic Neuralgiasupporting

confidence: 75%

Botulinum toxin: Non cosmetic and off-label dermatological uses

Alghamdi

Alghanemy

Joharji

et al. 2015

Journal of Dermatology & Dermatologic Surgery

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Botulinum toxin (BT-A) is a neurotoxin which is produced by the Gram-positive anaerobic bacterium Clostridium botulinum. The efficacy of Botulinum toxin in treating hyperhidrosis and the glabellar lines is well known and FDA approved.Because BT-A inhibits the release of acetylcholine and many other neurotransmitters such as norepinephrine and substance P at the level of nerve ending, this toxin has been used to treat a lot of dermatological disorders which are thought to be triggered by these neurotransmitters.In this article we are discussing the medical off-label uses of BT-A in dermatology.ª 2014 Production and hosting by Elsevier B.V. on behalf of King Saud University.

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Section: Post-herpetic Neuralgiasupporting

confidence: 75%

Botulinum toxin: Non cosmetic and off-label dermatological uses

Alghamdi

Alghanemy

Joharji

et al. 2015

Journal of Dermatology & Dermatologic Surgery

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“…A report that side-controlled axillary BTX-A injections in healthy volunteers has revealed that BTX-A could ameliorate or even improve body odor. 17 Li et al 7 have also compared the efficacy of decollement, combined tumescent liposuction and curettage, and BTX injection in the treatment of osmidrosis, and show that BTX injection is suitable for patients with minor or median odor. Thus, BTX-A injection was also advocated in this study.…”

Section: Discussionmentioning

confidence: 99%

Local injection of botulinum toxin A: An alternative therapy for axillary osmidrosis

Xie

Nie

Tan

2014

The Journal of Dermatology

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The objective of this study was to investigate the efficacy of local injection of botulinum toxin A for treating axillary osmidrosis. One hundred and fifty patients with axillary osmidrosis were randomly divided to receive botulinum toxin A injection treatment (50 U of botulinum toxin A was injected intracutaneously into 6-20 different sites within each axilla, n = 74) or surgical excision of the apocrine glands (n = 76). The patients were followed up for 1-3 months to analyze the therapeutic effect and complications of the two methods. The curative effect in patients with mild and moderate axillary osmidrosis was not significantly different between the botulinum toxin A injection group and operation group. However, for patients with severe axillary osmidrosis, surgery treatment seemed to be superior to botulinum toxin A treatment (P = 0.005). There was also no significant difference in the modified Dermatology Life Quality Index between the two treatments. Two cases showed complications related to hemorrhage and incision infection in the operation group. In conclusion, local injection of botulinum toxin A is a safe, fast and effective treatment for mild and moderate axillary osmidrosis, but the long-term effect remains to be further investigated.

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“…Such samples should effectively convey social information because axillary apocrine glands are considered to significantly influence the composition of socially relevant chemosignals (see Heckmann, Teichmann, Pause, & Plewig, 2003). The odor donors were asked to refrain from eating odorous foods and drinking alcohol (they were all non-smokers) and not to use perfumes and or personal hygiene products for three days prior to the experiment.…”

Section: Methodsmentioning

confidence: 99%

Partner’s body odor vs. relatives’ body odor: a comparison of female associations

Sorokowska

Butovskaya

Veselovskaya

2015

Polish Psychological Bulletin

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People positively appraise odors of individuals who are genetically different from themselves. Here we analyzed the relationship between perceived similarity of body odor to the judges’ relatives and their partners, and characteristics attributed to the odor donor. Seventy-six women were asked to smell one of the scents of twenty-nine men, and rate variables related to potential sexual interest in odor donor. We hypothesized that characteristics related to potential sexual interest would be associated with odor donors smelling similar to a partner, rather than with odor donors smelling similar to a relative. We found that perceived similarity to a partner’s scent was positively correlated with ratings of variables related to potential sexual interest in odor donor, whereas the resemblance to a close relative’s scent did not correlate with these assessments.

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Amelioration of Body Odor After Intracutaneous Axillary Injection of Botulinum Toxin A

Cited by 65 publications

References 23 publications

Botulinum toxin: Non cosmetic and off-label dermatological uses

Botulinum toxin: Non cosmetic and off-label dermatological uses

Local injection of botulinum toxin A: An alternative therapy for axillary osmidrosis

Partner’s body odor vs. relatives’ body odor: a comparison of female associations

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