Amebicides against Acanthamoeba castellanii: The Impact of Organism Models Used in Amebicide Assays
Leonardo Fernandes Geres,
Elena Sartori,
João Marcos dos Santos Neves
et al.
Abstract:Acanthamoeba castellanii is a free-living amoeba capable of causing keratitis in humans, with most cases related to contact lens wearers and surgical procedures. In addition, A. castellanii may cause pneumonia, granulomatous encephalitis, and skin lesions in immunocompromised individuals. Considering the lack of adequate treatment for acanthamoebiasis, the aim of this review is to assess relevant original articles that covered the current arsenal of drugs and models of organisms used in the field of experiment… Show more
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