Abstract:Antibiotics are prescribed in ∼21% of pediatric ambulatory visits nationally; of those, 16% are broad-spectrum cephalosporins (second-fourth generation). 1 Broad-spectrum cephalosporins are rarely recommended as first-line therapy for common pediatric infections, except in some instances of penicillin allergy. 2,3 Cefdinir in particular is frequently prescribed despite its less optimal pharmacokinetics and pharmacodynamics. 4,5 The overprescription of broad-spectrum cephalosporins leads to the development of a… Show more
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