1999
DOI: 10.1097/00126097-199903000-00014
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Ambulatory blood pressure as a predictor of target organ disease and outcome in the hypertensive patient

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Cited by 22 publications
(16 citation statements)
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“…Ambulatory BP predicts the risk of cardiovascular morbidity better than clinical BP [10,31]. Blunting of the normal drop in BP from day to night has emerged as a strong prognostic indicator of cardiovascular morbidity and mortality [9,20,21].…”
Section: Discussionmentioning
confidence: 99%
“…Ambulatory BP predicts the risk of cardiovascular morbidity better than clinical BP [10,31]. Blunting of the normal drop in BP from day to night has emerged as a strong prognostic indicator of cardiovascular morbidity and mortality [9,20,21].…”
Section: Discussionmentioning
confidence: 99%
“…1,2 In some patients with hypertension or chronic kidney disease however, BP fails to dip during night and these individuals have been called ''non-dippers'', in contrast with those with a normal nocturnal dip, who are called ''dippers''. 2,3 The clinical relevance of establishing a non-dipping BP pattern lies in its proven association with more severe hypertensive target organ damage and increased cardiovascular risk both in hypertensive and normotensive subjects. [4][5][6] Left ventricular hypertrophy, carotid intima-media thickening, microalbuminuria and cerebrovascular disease are more prevalent in non-dippers than in dippers.…”
Section: Introductionmentioning
confidence: 99%
“…Cross-sectional studies have indicated that target-organ damage is more pronounced in "nondippers" than in "dipper" patients with comparable clinical blood pressure. 4,5 Furthermore, a circadian pattern becomes obvious in the occurrence of acute cardiovascular diseases such as ischemia, infarction, stroke, and sudden death, 6 and investigators are using new chronotherapeutic approaches in antihypertensive therapy to exploit the knowledge of circadian rhythms to reduce these events. 7 Furthermore, it has been demonstrated that short-term (beatto-beat) variations of BP and HR contain information about the activity of the autonomic nervous system, 8 and power spectral analysis of these parameters shows promise for studying the mechanisms involved in cardiovascular disease.…”
mentioning
confidence: 99%