Ambulatory 24-hour fast using flexible insulin therapy in patients with type 1 diabetes

Vigeral, C.; Sola-Gazagnes, A.; Nejjar, S.; M’Bemba, J.; Slama, G.; Elgrably, F.; Larger, Étienne

doi:10.1016/j.diabet.2011.06.002

Cited by 3 publications

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Addressing these lifestyle changes is essential and can become a challenge in the daily management of diabetes. The majority of clinical studies addressing fasting have focused on type 2 diabetes [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] while studies in patients with type 1 diabetes have focused mainly on modes of treatment and risks of complications during fasting [14] , [15] , [16] , [17] , [18] , [19] , [20] . Data on habits and attitudes of patients with diabetes during Ramadan is limited.…”

Section: Discussionmentioning

confidence: 99%

Attitudes and habits of patients with type 1 diabetes during fasting Ramadan

Alamoudi

Alsubaiee

Alqarni

et al. 2018

Journal of Clinical & Translational Endocrinology

View full text Add to dashboard Cite

ObjectiveFasting Ramadan is associated with changes in lifestyle patterns of patients with diabetes who choose to perform fasting. We aimed to determine the attitude and habits of patients with type 1 diabetes during fasting Ramadan.MethodsThe study comprised a prospective cohort of patients with type 1 diabetes who were on insulin pump or multiple daily insulin injections (MDI) regimen. Patient questionnaires included the frequency of self-monitoring of blood glucose (SMBG), the need to make changes in insulin regimen by patients, timings of insulin administration, performing carbohydrate counting and levels of physical activity.ResultsA total of 156 patients were studied (61 patients on insulin pump and 95 patients on MDI). Patients on pump therapy performed SMBG more frequently than those on MDI regimen (4.8 ± 1.4 and 3.7 ± 1.7 times per day, respectively, P = 0.001) and were more likely to perform carbohydrate counting (32.7% and 8.4% of pump and MDI patients, respectively, P < 0.001). There was no difference in the percentage of patients who made changes in insulin doses (74.5% of the pump group and 77.3% of MDI patients) or those who had any level of physical activity (12.5% of the pump group and 21.1% of the MDI group). The timing of administering meal insulin in relation to sunset meal was variable with a preference to taking the injection immediately at sunset. There was no difference in glucose control between both groups as measured by frucotsamine levels or the number of days that patients have to stop fasting.ConclusionFasting Ramadan is associated with significant and variable changes in the attitude and behaviors of patients with type 1 diabetes with no difference in glucose control between patients on insulin pump or MDI regimen. Further studies are needed to define the role of education and its effect on these attitudes and patient care in this population.ClinicalTrials.gov Identifier: NCT01941238.

show abstract

Section: Discussionmentioning

confidence: 99%

Attitudes and habits of patients with type 1 diabetes during fasting Ramadan

Alamoudi

Alsubaiee

Alqarni

et al. 2018

Journal of Clinical & Translational Endocrinology

View full text Add to dashboard Cite

show abstract

Insulinothérapie fonctionnelle : un modèle d’approche éducative pour les patients ayant un diabète de type 1

Mohn

Kavan

Bourcelot

et al. 2012

Médecine des Maladies Métaboliques

View full text Add to dashboard Cite

Model-Based Tool for Personalized Adjustment of Basal Insulin Supply in Patients With Intensified Conventional Insulin Therapy

Vogt¹,

Thomas

Fritzsche³

et al. 2019

J Diabetes Sci Technol

View full text Add to dashboard Cite

Background: The decisive factor in successful intensive insulin therapy is the ability to deliver need-based-adjusted nutrition-independent insulin dosages at the closest possible approximation to the physiological insulin level. Because this basal insulin requirement is strongly influenced by the patient’s lifestyle, its subtlety is of great importance. This challenge is very different between patients with type 1 diabetes and those with insulin-dependent type 2 diabetes. Furthermore, it is more difficult to finetune a basal insulin dosage with intensified conventional insulin therapy (ICT), due to delayed insulin delivery, compared to insulin pump therapy, which provides continuous delivery of small doses of exclusively short-acting insulin. In all cases, the goal is to achieve an optimal basal delivery rate. Method: We hypothesized that this goal could be achieved with a modeling tool that determined the optimal basal insulin supply based on the patient’s anamnestic data and monitored glucose values. This type of modeling tool has been used in health insurance programs in Germany to improve insulin control in patients that receive ICT. Results: Our retrospective data analysis showed that this modeling tool provided a significant improvement in metabolic control, significant reductions in HbA1c and Q scores, and improved time-in-range values, with reduced daily insulin levels. Conclusion: The model-based basal rate test could provide additional data of the actual effect of the basal insulin adjustment in intensified insulin treated diabetes to the physician or treatment team.

show abstract

Ambulatory 24-hour fast using flexible insulin therapy in patients with type 1 diabetes

Cited by 3 publications

References 21 publications

Attitudes and habits of patients with type 1 diabetes during fasting Ramadan

Attitudes and habits of patients with type 1 diabetes during fasting Ramadan

Insulinothérapie fonctionnelle : un modèle d’approche éducative pour les patients ayant un diabète de type 1

Model-Based Tool for Personalized Adjustment of Basal Insulin Supply in Patients With Intensified Conventional Insulin Therapy

Contact Info

Product

Resources

About