Ambient temperature and risk of urinary tract infection in California: A time-stratified case-crossover study using electronic health records

Elser, Holly; Rowland, Sebastian T.; Tartof, Sara Y.; Parks, Robbie M.; Bruxvoort, Katia; Morello‐Frosch, Rachel; Robinson, Sarah; Pressman, Alice; Wei, Rong; Casey, Joan A.

doi:10.1016/j.envint.2022.107303

Cited by 12 publications

(12 citation statements)

References 69 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our cohort, ER visits due to UTI were more prevalent in the high-income group than in the other two income groups in both the total and elderly populations. This result is in contrast to the ndings of previous studies in California that found no clear relationship between individual or community-level socioeconomic status and UTI diagnosis rate [10,26]. Nevertheless, it could be conjectured that individuals with lower socioeconomic status are more vulnerable to UTI and hot temperatures owing to poorer hygiene and/or poorer occupational conditions (e.g., more outdoor economic activities, working long hours) [27].…”

Section: Discussioncontrasting

confidence: 74%

“…Additionally, two single-city studies in Adelaide, Australia (2003-2014) and Beijing, China (2013-2018) also reported a positive association between hot temperatures and ER visits due to UTI [20,22]. However, a recent study of two California health care systems (2015-2017) found no signi cant association between temperature and outpatient UTI diagnosis in the summer [10]. To the best of our knowledge, this is the largest study estimating the national risk of summer temperature on severe UTI based on a nationwide cohort that represents the entire population (including all ages), with evidence for various individual-level risk factors (age, sex, household income, and diabetes history).…”

Section: Discussionmentioning

confidence: 99%

“…Additionally, limited uid intake, dehydration, and related decreases in urine production and clearance of urinary pathogens have been suggested as environmental risk factors for UTIs [8]. As an environmental stressor, the relationship between high ambient temperature and UTI has been examined in some recent studies [9][10][11][12]. Nevertheless, the number of related studies is much smaller than those on heat and cardiovascular/respiratory diseases, and most previous studies have been based on a certain population (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…Nevertheless, the number of related studies is much smaller than those on heat and cardiovascular/respiratory diseases, and most previous studies have been based on a certain population (e.g. Medicare population [older adults] or females) [9,12], Western countries [9][10][11][12], which have different genes, diets, and environmental conditions compared to Eastern countries. Moreover, most previous studies have not investigated relevant socioeconomic factors and temporal changes in the risk of heat on UTI.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Summer temperature and emergency room visits due to urinary tract infection in South Korea: a national time-stratified case-crossover study

Park,

Lee,

Kang

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Although urinary tract infection (UTI) is a common and severe public health concern, and there are clear biological mechanisms between UTI and hot temperatures, few studies have addressed the association between hot temperatures and UTI. Methods We designed a time-stratified case-crossover study using a population-representative sample cohort based on the national health insurance system (NHIS) in South Korea. We obtained all NHIS-based hospital admissions through the emergency room (ER) due to UTI (using a primary diagnostic code) from 2006 to 2019. We assigned satellite-based reanalyzed daily summer (June to September) average temperatures as exposures, based on residential districts of beneficiaries (248 districts in South Korea). The conditional logistic regression was performed to evaluate the association between summer temperature and UTI outcome. Results Among 4,450 ER visits due to UTI were observed during the summer between 2006 and 2019 among 1,131,714 NHIS beneficiaries. For 20% increase in summer temperature (moving average of 0–2 lag days), the odd ratio (OR) was 1.05 (95% CI: 1.02, 1.09) in the total population, and the association was more prominent in the elderly (people aged 65y or older; OR: 1.09, 95% CI: 1.04, 1.15), females (OR: 1.10, 95% CI: 1.04, 1.17), and people with diabetes history (OR: 1.12, 95% CI: 1.05, 1.19). The effect modification by household income was different in the total and elderly populations. Furthermore, the association between summer temperature and UTI increased during the study period in the total population. Conclusions Higher summer temperatures were associated with an increased risk of ER admissions for UTI. The results are consistent with the hypothesis that higher summer temperatures increase the risk of severe UTIs.

show abstract

Section: Discussioncontrasting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Summer temperature and emergency room visits due to urinary tract infection in South Korea: a national time-stratified case-crossover study

Park,

Lee,

Kang

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…As a result of climate change, the already established U.S. kidney stone “belt” in southeast regions of the country seems to be expanding northward [ 40 ]. Increases in mean daily temperatures were also associated with higher outpatient urinary tract infection cases among women in a case-crossover report in California [ 41 ]. These studies demonstrate seasonality in kidney diseases, putting forth warmer climates as a potential risk factor.…”

Section: Kidney Health In Extreme Temperature Conditionsmentioning

confidence: 99%

Molecular Challenges and Opportunities in Climate Change-Induced Kidney Diseases

Luna-Cerón,

Pherez-Farah,

Krishnan-Sivadoss

et al. 2024

Biomolecules

View full text Add to dashboard Cite

As temperatures continue to modify due to weather changes, more regions are being exposed to extreme heat and cold. Physiological distress due to low and high temperatures can affect the heart, blood vessels, liver, and especially, the kidneys. Dehydration causes impaired cell function and heat itself triggers cellular stress. The decline in circulating plasma volume by sweat, which stresses the renal and cardiovascular systems, has been related to some molecules that are crucial players in preventing or provoking cellular damage. Hypovolemia and blood redistribution to cutaneous blood vessels reduce perfusion to the kidney triggering the activation of the renin–angiotensin–aldosterone system. In this review, we expose a deeper understanding of the modulation of molecules that interact with other proteins in humans to provide significant findings in the context of extreme heat and cold environments and renal damage reversal. We focus on the molecular changes exerted by temperature and dehydration in the renal system as both parameters are heavily implicated by weather change (e.g., vasopressin-induced fructose uptake, fructogenesis, and hypertension). We also discuss the compensatory mechanisms activated under extreme temperatures that can exert further kidney injury. To finalize, we place special emphasis on the renal mechanisms of protection against temperature extremes, focusing on two important protein groups: heat shock proteins and sirtuins.

show abstract

Association between diurnal temperature range and outpatient visits for urticaria disease in Lanzhou, China: a distributed lag nonlinear analysis

Wu,

Zhang,

Luo

et al. 2023

Int Arch Occup Environ Health

View full text Add to dashboard Cite

Ambient temperature and risk of urinary tract infection in California: A time-stratified case-crossover study using electronic health records

Cited by 12 publications

References 69 publications

Summer temperature and emergency room visits due to urinary tract infection in South Korea: a national time-stratified case-crossover study

Summer temperature and emergency room visits due to urinary tract infection in South Korea: a national time-stratified case-crossover study

Molecular Challenges and Opportunities in Climate Change-Induced Kidney Diseases

Association between diurnal temperature range and outpatient visits for urticaria disease in Lanzhou, China: a distributed lag nonlinear analysis

Contact Info

Product

Resources

About