Ambient nitrogen dioxide pollution and spread ability of COVID-19 in Chinese cities

Yao, Ye; Pan, Jinhua; Liu, Zhixi; Meng, Xia; Wang, Weibing; Kan, Haidong

doi:10.1101/2020.03.31.20048595

Cited by 18 publications

(22 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In China, in Hubei province, brand new time analyses give preliminary evidence of a correlation between high levels of NO2 and 12day delayed virus outbreaks 49 and other PM covariates 50,51 . In the U.S.A., levels of PM2.5 have just been found responsible for 20-time higher mortality rate by COVID-19, a rate much higher than other demographic co-variables 52 .…”

Section: Discussionmentioning

confidence: 99%

Early evidence of a higher incidence of COVID-19 in the air-polluted regions of eight severely affected countries

Pansini

Fornacca

2020

Preprint

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Early evidence of a higher incidence of COVID-19 in the air-polluted regions of eight severely affected countries

Pansini

Fornacca

2020

Preprint

View full text Add to dashboard Cite

show abstract

“…of the SARS-CoV-2 outbreak, there is evidence of a significant positive correlation between air pollution levels and higher morbidity and mortality rates from COVID-19. Yao et al 6 assessed the correlation between the spread of COVID-19 and NO 2 pollution. They conducted a cross-sectional analysis to examine the spatial associations of NO 2 and COVID-19 transmission rates (R 0 ), and longitudinal analyses to examine day-by-day spread-pollution associations in the cities.…”

mentioning

confidence: 99%

“…In other words, the higher the NO 2 pollution, the greater the spread of SARS-CoV-2 (and onset of COVID-19). 6 The same group conducted cross-sectional analyses to examine the spatial associations of daily PM 2.5 and PM 10 concentrations with mortality rates from COVID-19 in China. Their results confirm that increased concentrations of PM 2.5 and PM 10 are linked to higher death rates from COVID-19 (P 5.011 and P 5.015, respectively) on a spatial scale.…”

mentioning

confidence: 99%

Air pollution, racial disparities, and COVID-19 mortality

Brandt

Beck

Mersha

2020

Journal of Allergy and Clinical Immunology

136

125

View full text Add to dashboard Cite

Since late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions of people worldwide and resulted in more than 200,000 coronavirus disease 2019 (COVID-19) deaths. Emerging data suggest that elderly people as well as individuals with underlying health conditions are at a higher risk of hospitalization and death. 1-3 Interestingly, the Centers for Disease Control and Prevention's list of risk factors for severe COVID-19 (Fig 1) largely overlap with the list of diseases that are known to be worsened by chronic exposure to air pollution, including diabetes, heart diseases, and chronic airway diseases, such as asthma, lung cancer, and chronic obstructive pulmonary disease. 3 In this editorial, we highlight potential links between exposure to air pollution and COVID-19 severity, and we also hypothesize that disparate exposure to air pollution is one of the factors that contribute to the disproportionate impact COVID-19 is having on inner-city racial minorities. Air pollution is a complex mixture of particulate matter smaller than 2.5 or 10 mm (PM 2.5 , PM 10), nitric dioxide (NO 2), carbon monoxide (CO), ozone (O 3), and volatile organic compounds derived from vehicular traffic, industrial emissions, and indoor pollutants. Given overwhelming evidence linking chronic exposure to air pollution with increased morbidity and mortality across a range of cardiopulmonary diseases, 4 there is growing concern that air pollution may also contribute to COVID-19 severity, by directly affecting the lungs' ability to clear pathogens and indirectly by exacerbating underlying cardiovascular or pulmonary diseases. Such a link was reported during the 2003 SARS outbreak in China, where a positive association was observed between both acute and chronic pollution measures from the air pollution index (CO, NO 2 , SO 2 , O 3 , and PM 10) and SARS case-fatality rates. 5 Now, preliminary data are suggesting similar associations for COVID-19. In cities of China's Hubei province, the epicenter

show abstract

“…First observations report a positive association between ambient concentrations of NO2 and COVID-19 pandemic across Europe, China and U.S.A (Guan et al, 2020;Ogen, 2020;Pansini and Fornacca, 2020;Travaglio et al, 2020;Yao et al, 2020a;Zhu et al, 2020). As well as for particulates matter, but the paper of Ma et al, (2020) provides different findings, reporting no association between NO2 and mortality rate in in Wuhan, China.…”

Section: Nitrogen Dioxide (No2)mentioning

confidence: 99%

“…A cross-sectional study was performed by Yao et al(2020a) to evaluate the spatial association of NO2 levels with R0 of COVID-19, as well, a longitudinal study to evaluate a day-by-day association between NO2 and R0 across 63 Chinese cities, collecting COVID-19 confirmed case information and hourly NO2 data from the national databases. The cross-sectional study showed a positive association of R0 with NO2 in all cities (χ2=10.18 and p=0<0.05).…”

Section: Nitrogen Dioxide (No2)mentioning

confidence: 99%

A First Review to Explore the Association of Air Pollution (PM and NO<sub>2</sub>) on Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)

Copat¹,

Cristaldi²,

Fiore³

et al. 2020

Preprint

View full text Add to dashboard Cite

A new coronavirus (SARS-CoV-2) have determined a pneumonia outbreak in China (Wuhan and Hubei) on December 2019. While pharmaceutical and non-pharmaceutical intervention strategies are strengthened worldwide, the scientific community has been studying the risk factors associated with SARS-Cov-2, to enrich epidemiological information. For a long time, before the industrialized era, air pollution has been a real and big health concern and it is today a very serious environmental risk for many diseases and anticipated deaths in the world. It has long been known that air pollutants increasing the invasiveness of pathogens for humans by acting as a carrier and making people more sensitive to pathogens through a negative influence on the immune system. Based on scientific evidences, the hypothesis that air pollution, resulting from a combination of factors such as meteorological data, level of industrialization as well as regional topography, can acts both as an infection carrier as a harmful factor of the health outcomes of COVID-19 disease has been raised recently. This hypothesis is turning in scientific evidence, thanks to the numerous studies that have been launched all over the world.With this review, we want to provide a first unique view of all the first epidemiological studies relating the association between air pollution and SARS-CoV-2. The Authors, who first investigated this association, although with great effort and rapidity of analysis dictated by a global emergency, often used different research methods or not all include confounding factors whenever possible. In addition, to date incidence data are underestimated in all countries, and to a lesser extent also mortality data. For this reason, the cases included in the considered studies cannot be considered real. Although it determines important limitations for direct comparison of results, and more studies are needed to strengthen scientific evidences and support firm conclusions, major findings are consistent, highlighting the important contribution of PM2.5 and NO2 on the COVID-19 spread and with a less extent also PM10.

show abstract

Ambient nitrogen dioxide pollution and spread ability of COVID-19 in Chinese cities

Abstract: none

Cited by 18 publications

References 5 publications

Early evidence of a higher incidence of COVID-19 in the air-polluted regions of eight severely affected countries

Early evidence of a higher incidence of COVID-19 in the air-polluted regions of eight severely affected countries

Air pollution, racial disparities, and COVID-19 mortality

A First Review to Explore the Association of Air Pollution (PM and NO<sub>2</sub>) on Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)

Contact Info

Product

Resources

About