2021
DOI: 10.6065/apem.2142132.066
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Ambient air pollution and endocrinologic disorders in childhood

Abstract: Ambient air pollution has been proposed as an important environmental risk factor that increases global mortality and morbidity. Over the past decade, several human and animal studies have reported an association between exposure to air pollution and altered metabolic and endocrine systems in children. However, the results for these studies were mixed and inconclusive and did not demonstrate causality because different outcomes were observed due to different study designs, exposure periods, and methodologies f… Show more

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Cited by 9 publications
(6 citation statements)
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References 97 publications
(174 reference statements)
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“…Variations in Tvol and goiter rates in children have been reported even in long-standing iodine-sufficient countries ( Table 5 ) ( 18 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ). Genetic and environmental factors, including obesity, dietary habits, and exposure to iodine and other goitrogens, can affect the differences in Tvol among countries ( 18 , 28 , 29 ). Although the WHO has adopted international reference values for Tvol ( 3 ), significant differences among countries suggest the need for population-specific criteria, especially in countries with long-standing iodine sufficiency ( 7 , 18 , 30 ).…”
Section: Discussionmentioning
confidence: 99%
“…Variations in Tvol and goiter rates in children have been reported even in long-standing iodine-sufficient countries ( Table 5 ) ( 18 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ). Genetic and environmental factors, including obesity, dietary habits, and exposure to iodine and other goitrogens, can affect the differences in Tvol among countries ( 18 , 28 , 29 ). Although the WHO has adopted international reference values for Tvol ( 3 ), significant differences among countries suggest the need for population-specific criteria, especially in countries with long-standing iodine sufficiency ( 7 , 18 , 30 ).…”
Section: Discussionmentioning
confidence: 99%
“…Air pollution may be associated with neuroendocrine complications, development of Type I diabetes mellitus, high blood pressure, obesity, congenital hypothyroidism, and insulin resistance in offspring (Heo & Kim, 2021; Shang et al, 2019; Zhang et al, 2018). Air pollution may affect central nervous system development of the developing fetus, decreased inhibitory control in school-aged children, and development of attention-deficit hyperactivity disorder and autism (Dutheil et al, 2021; Guxens et al, 2018; Zhang et al, 2022).…”
Section: Direct and Indirect Mechanisms Affecting Maternal Child Healthmentioning
confidence: 99%
“…Pregnant women exposed to air pollutants, particularly dusty particulate matter, may experience adverse birth outcomes such as preterm birth, low birth weight, and developmental abnormalities. Children exposed to air pollution have a higher risk of impaired lung function, cognitive deficits, behavioral problems, and developmental disorders (Vrijheid et al, 2012;Raz et al, 2013;Roberts et al, 2013;Sram et al, 2013;Xu et al, 2014;Forns et al, 2018;Kerin et al, 2018;Jo et al, 2019;Qiu et al, 2019;Carvalho et al, 2020;Ferrari et al, 2020;McGuinn et al, 2020;Thygesen et al, 2020;Volk et al, 2020;Heo and Kim, 2021;Johnson et al, 2021;Decrue et al, 2023;Lee et al, 2023).…”
Section: Development Effectsmentioning
confidence: 99%