Amaranthus cruentus L. Seed Oil counteracts UVA - Radiation – induced inhibition of Collagen Biosynthesis and Wound Healing in Human Skin Fibroblasts
Katarzyna Wolosik,
Magda Chalecka,
Jerzy Palka
et al.
Abstract:The effect of Amaranthus cruentus L. seed oil (AmO) on collagen biosynthesis and wound healing was studied in cultured human dermal fibroblasts exposed to UVA radiation. It has been found that UVA radiation inhibited collagen biosynthesis, prolidase activity, expression of β1-integrin receptor, phosphorylated ERK1/2 and TGF-β, while increased the expression of p38 kinase. The AmO at 0.05-0.15% counteracted the above effects induced by UVA radiation in fibroblasts. UVA radiation also induced the expression and … Show more
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