2018
DOI: 10.1016/j.freeradbiomed.2018.05.057
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Amaranth oil in prevalent pulmonary arterial hypertension: changes in fatty acid panel and products of lipid peroxidation

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“…For example, globulin 11S [45] showed a potential to modulate the angiotensin system [through inhibition of angiotensin-I-converting enzyme (ACE)] tested to be resistant to gastrointestinal hydrolysis in a simulated digestive environment [46], suggesting resistance to peptic hydrolysis by human digestion. Seed protein hydrolysates also showed antihypertensive effect in vivo [47], which was also the case for amaranth oil in pulmonary arterial hypertension, although a lot of clarification is required to this respect [48]. Other in vitro studies showed that the pure peptides of amaranth inhibit cellular markers associated with the development of atherosclerosis [49] (a disease strongly linked to coronary artery disease [50]).…”
Section: Cardiovascular System Healthmentioning
confidence: 86%
“…For example, globulin 11S [45] showed a potential to modulate the angiotensin system [through inhibition of angiotensin-I-converting enzyme (ACE)] tested to be resistant to gastrointestinal hydrolysis in a simulated digestive environment [46], suggesting resistance to peptic hydrolysis by human digestion. Seed protein hydrolysates also showed antihypertensive effect in vivo [47], which was also the case for amaranth oil in pulmonary arterial hypertension, although a lot of clarification is required to this respect [48]. Other in vitro studies showed that the pure peptides of amaranth inhibit cellular markers associated with the development of atherosclerosis [49] (a disease strongly linked to coronary artery disease [50]).…”
Section: Cardiovascular System Healthmentioning
confidence: 86%