Abstract:Background
Acute lung injury and the acute respiratory distress syndrome are characterized by pulmonary inflammation, reduced endothelial barrier integrity and filling of the alveolar space with protein rich edema fluid and infiltrating leukocytes. Animal models are critical to uncovering the pathologic mechanisms of this devastating syndrome. Intravital imaging of the intact lung via two-photon intravital microscopy has proven a valuable method to investigate lung injury in small rodent models… Show more
Intravital imaging (IVI), used for revealing real-time dynamics of biological systems, often suffers from noise. Here, we, for the first time, compare various denoising methods to determine the best algorithms for IVI in several tissues.
Intravital imaging (IVI), used for revealing real-time dynamics of biological systems, often suffers from noise. Here, we, for the first time, compare various denoising methods to determine the best algorithms for IVI in several tissues.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.