Alveolar ridge augmentation in Macaca fascicularis using polysulfone with and without demineralized bone powder

Salama, Fouad; Sharawy, Mohamed

doi:10.1016/0278-2391(89)90007-4

Cited by 12 publications

(6 citation statements)

References 19 publications

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“…This problem has stimulated the search of synthetic, inorganic products for use in ridge augmentation and other reconstructive applications. Existing results are available using hydroxyapatite (Cohen, 1984;Greenstein et al, 1985;Tardieu, 1986;Bahat et al, 1987;Mercier, 1988;Sussman, 1990), bioactive glass ceramics (Shaoan et al, 1989), and polysulfone (Salama et al, 1989).…”

Section: Introductionmentioning

confidence: 99%

Bone augmentation using a synthetic bone graft in dogs

Hürzeler¹,

Einsele²,

Leupolz³

et al. 1994

J of Oral Rehabilitation

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The aim of this investigation was to evaluate clinically and histologically the use of a synthetic bone graft (Ionogran) alone and in combination with guided bone regeneration (GBR) for alveolar ridge augmentation. Five beagle dogs were used in this study. Prior to the augmentation procedure the maxillary and mandibular second, third and fourth premolars were extracted. Three months after the extractions, impressions from the area of the ridges were taken. Particles of Ionogran were then placed under mucoperiosteal flaps in each quadrant. On the experimental sites, an expanded polytetrafluoroethylene barrier was placed between the flap and the particles. Impressions were retaken at 1 and 3 months after surgery. Three months after surgery, the animals were sacrificed and specimens were prepared for histological evaluation. Computer-assisted volumetric analyses from the casts revealed an increase in ridge volume from baseline in both groups at 1 and 3 months. There was no difference in the height of the augmentation between the test and control sites. The histological results of this study indicate that this new synthetic bone graft appears to be a safe biocompatible grafting material. There were no apparent histological differences between the graft alone and graft/GBR sites. In both groups, however, graft particles were surrounded by dense fibrous connective tissue and bone formation was limited to the graft bone interface.

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Section: Introductionmentioning

confidence: 99%

Bone augmentation using a synthetic bone graft in dogs

Hürzeler¹,

Einsele²,

Leupolz³

et al. 1994

J of Oral Rehabilitation

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show abstract

“…The viability levels were same even after 96 h. The incorporation of CQ and BM, in SPAEK-CQ and SPAEK-BM, respectively, did not bring about any significant change in the viability in the periods of 48 and 96 h. The results indicate that the sponge–phytochemical system is highly biocompatible. Salama and Sharawy 26 have evaluated porous polysulphone for such applications and attempted to induce bone formation by incorporation of demineralized bone matrix (DBM) along with porous polysulphone sponges.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of phytochemical-incorporated porous polymeric sponges for bone tissue engineering: A novel perspective

Raghavan

Somanathan

Sastry

2013

Proc Inst Mech Eng H

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Porous polymeric scaffolds are extensively studied for delivery of bone growth factors. Since phytochemicals are known to produce changes in cell signalling and other metabolic pathways, osteogenic phytochemicals, that is, extracts of Cissus quadrangularis and Butea monosperma, are incorporated into sulphonated poly(aryl ether ketone) sponges. The results have shown that the scaffolds with phytochemicals enhanced the proliferation and alkaline phosphatase activity of the cells compared to cells treated on scaffolds without phytochemicals. Hence, these phytochemicals can be evaluated to augment, if not substitute the use of bone morphogenetic proteins in scaffolds.

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“…Polysulfones, a class of amorphous thermoplastic polymers, were proposed as orthopedic and implant material, with promising results in animal models [30,31], for alveolar ridge augmentation in conjunction with a demineralized bone powder [32] or as denture base reinforcement [33]. Titanium oxide presents excellent biocompatibility [34] and recently proved positive influence in osteoblast adhesion and differentiation [35,36].…”

Section: Introductionmentioning

confidence: 99%

Non-Resorbable Nanocomposite Membranes for Guided Bone Regeneration Based on Polysulfone-Quartz Fiber Grafted with Nano-TiO2

et al. 2019

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The polymer-inorganic nanoparticles composite membranes are the latest solutions for multiple physicochemical resistance and selectivity requirements of membrane processes. This paper presents the production of polysulfone-silica microfiber grafted with titanium dioxide nanoparticles (PSf-SiO2-TiO2) composite membranes. Silica microfiber of length 150–200 μm and diameter 12–15 μm were grafted with titanium dioxide nanoparticles, which aggregated as microspheres of 1–3 μm, applying the sol-gel method. The SiO2 microfibers grafted with nano-TiO2 were used to prepare 12% polysulfone-based nanocomposite membranes in N-methyl pyrrolidone through the inversion phase method by evaporation. The obtained nanocomposite membranes, PSf-SiO2-TiO2, have flux characteristics, retention, mechanical characteristics, and chemical oxidation resistance superior to both the polysulfone integral polymer membranes and the PSf-SiO2 composite membranes. The antimicrobial tests highlighted the inhibitory effect of the PSf-SiO2-TiO2 composite membranes on five Gram (-) microorganisms and did not allow the proliferation of Candida albicans strain, proving that they are suitable for usage in the oral environment. The designed membrane met the required characteristics for application as a functional barrier in guided bone regeneration.

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Alveolar ridge augmentation in Macaca fascicularis using polysulfone with and without demineralized bone powder

Cited by 12 publications

References 19 publications

Bone augmentation using a synthetic bone graft in dogs

Bone augmentation using a synthetic bone graft in dogs

Evaluation of phytochemical-incorporated porous polymeric sponges for bone tissue engineering: A novel perspective

Non-Resorbable Nanocomposite Membranes for Guided Bone Regeneration Based on Polysulfone-Quartz Fiber Grafted with Nano-TiO2

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