Alveolar Rhabdomyosarcoma of the Greater Omentum in a Dog

Sarnelli, R; Grassi, Francesco; Romagnoli, Simona

doi:10.1177/030098589403100412

Cited by 16 publications

(21 citation statements)

References 2 publications

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“…However, there seems to be a trend of similarity with what has been reported in humans, regarding the fact that the majority of rMSs in dogs have occurred in tissues that normally do not contain striated-muscle cells, such as the pharynx, gingiva, urethra, trachea, larynx and the jawbone (Seibold, 1974;Sarnelli et al,1994;yanoff et al, 1996;Ginel et al, 2002;, Illanes, 2002;Kobayashi et al, 2004;Suzuki et al, 2006;Bae et al, 2007;Murakami et al, 2010). A few cases of canine rMSs have been reported to arise from striated muscles (Worley and Gorham, 1954;Gonin-Jmaa et al, 1996;Kim et al, 1996;Lascelles et al, 1998;Pérez et al, 1998;Cooper and Valentine, 2002;Machida et al, 2003;Brockus and Myers, 2004;Akkoc et al, 2006;Aupperle et al, 2007;Nakaichi et al, 2007;Chapman et al, 2008;yhee et al, 2008;yamate et al, 2011) and only some of them were further classified.…”

Section: Introductionmentioning

confidence: 64%

Rhabdomyosarcomas arising from striated muscles in elderly dogs: pathological features of 4 cases

Brellou

Psychas

Vlemmas

2017

J Hellenic Vet Med Soc

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Primary rhabdomyosarcomas are rare in dogs. Based on their classification, embryonal rhabdomyosarcoma is the most common, while alveolar and especially pleomorphic types occur less often. Four cases diagnosed as primary canine rhabdomyosarcomas of striated muscles were retrieved from our files. All the animals were cross-breeds, aged over 8 years. Two of them had died after developing disseminated intravascular coagulation and gastric ulcer, respectively, and two others were euthanized. Of those two, one had been admitted with neurological and cardiovascular symptoms and one with disseminated intravascular coagulation. Necropsy was performed and tissue samples were collected for histological and immunohistochemical examination. The first case was diagnosed as mixed rhabdomyosarcoma, pleomorphic type in the heart and the diaphragm and alveolar type in the lungs and the spleen. The three other cases were of alveolar type. One showed primary cardiac and oesophageal origin, with metastases in the skeletal muscles and non striated muscle tissues, one had primary cardiac, with mitral valve involvement, and skeletal muscle origin, with metastases in extra striated muscle tissues and one showed only skeletal muscle localization. Immunohistochemical examination revealed myoglobin and α-sarcomeric actin in tumour cells.

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Section: Introductionmentioning

confidence: 64%

Rhabdomyosarcomas arising from striated muscles in elderly dogs: pathological features of 4 cases

Brellou

Psychas

Vlemmas

2017

J Hellenic Vet Med Soc

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“…To the authors' knowledge, in dogs, four cases of alveolar rhabdomyosarcoma (Seibold Sarnelli et al 1994;Kim et al 1996;Bae et al 2007) have been reported, which occurred in the gingiva, urinary bladder, genital tract, retroperitoneal cavity, left maxillary area and greater omentum, and these cases were confirmed via myoglobin immunohistochemistry. Myogenin is considered as the most critical marker for human rhabdomyosarcoma (Dias et al 2000).…”

Section: Discussionmentioning

confidence: 85%

“…Cross striations can be difficult to demonstrate in poorly differentiated alveolar rhabdomyosarcomas (Sarnelli et al 1994). In this case, we tried to detect cross-striations using PTAH staining; however, no cross-striations were observed in the neoplastic cells, which were considered as poorly differentiated cells.…”

Section: Discussionmentioning

confidence: 98%

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Alveolar rhabdomyosarcoma in a dog confirmed using myogenin immunohistochemistry: a case report

Park¹,

Lee²,

Kim³

et al. 2016

Vet. Med. - Czech

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ABSTRACT:A large mass from the right forelimb of a five-year-old, male, Maltese dog, was resected surgically and examined histopathologically. Grossly, the 4 × 6 cm mass was well-demarcated and firm. Microscopically, the mass was characterised by neoplastic mononuclear cells with large round hyperchromatic nuclei and scant cytoplasm. The neoplastic tumour cells were separated by thick or thin collagen septa and were arranged in an alveolar pattern forming cell nests. Immunohistochemical detections of the tumour revealed positive reactions for vimentin, desmin and myogenin, but the tumour was negative for alpha smooth muscle actin (α-SMA), S-100, CD3, CD79a, CD68, cytokeratin 8 (CK8) and cytokeratin 18 (CK18). These results showed that the tumour cells originated from skeletal muscle; therefore, the tumour was diagnosed as an alveolar rhabdomyosarcoma.

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“…Many authors reported occasional cases of finding the rhabdomyosarcoma in the heart atrium and chamber (Krotje et al 1990;Gonin-Jmaa et al 1996;Perez et al 1998), perineal area (Ueno et al 2002), parameningeal area (Illanes 2002), tongue (Lascelles et al 1998), gingiva (Kim et al 1996) or greater omentum (Sarnelli et al 1994). Yanoff et al (1996), Block et al (1995) and Hendersen et al (1991) report rhabdomyosarcomas causing tracheal defects.…”

Section: Discussionmentioning

confidence: 99%

Retrobulbar Rhabdomyosarcoma in a Hovawart

Nečas¹,

Raušer²,

Tichy³

et al. 2003

Acta Vet. Brno

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Neãas A., P. Rau‰er, F. Tich˘, P. Kohout, H. Kecová: Retrobulbar Rhabdomyosarcoma in a Hovawart. Acta Vet. Brno 2003, 72: 399-404. This clinical case study describes a three-year-old female Hovawart dog presented due to a unilateral exophtalmos and diagnosed with a retrobulbar tumour arising from m. rectus ventralis using ultrasound and computer tomography. The tumour was cytologically classified to be of a malignant mesenchymal kind. Modification of lateral orbitotomy with canthotomy was performed and the circumscribed tumour resected in its entirety. After healing, the eye was like the healthy contralateral one. Three months later, however, there was a relapse of the same extent and the patient was euthanised on the owner´s request. Rhabdomyosarcoma was confirmed by repeated histological examinations. Tumour, dog, orbitotomy

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Alveolar Rhabdomyosarcoma of the Greater Omentum in a Dog

Cited by 16 publications

References 2 publications

Rhabdomyosarcomas arising from striated muscles in elderly dogs: pathological features of 4 cases

Rhabdomyosarcomas arising from striated muscles in elderly dogs: pathological features of 4 cases

Alveolar rhabdomyosarcoma in a dog confirmed using myogenin immunohistochemistry: a case report

Retrobulbar Rhabdomyosarcoma in a Hovawart

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