Alveolar bone graft with Platelet Rich Plasma in cleft alveolus

Gupta, Chandan; Mehrotra, Divya; Mohammad, Shadab; Khanna, Vaibhav; Singh, Gulshan; Singh, Geeta; Chellappa, Arul A.L.; Passi, Deepak

doi:10.1016/j.jobcr.2013.02.002

Cited by 26 publications

(27 citation statements)

References 14 publications

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“…This result agreed with Chandan et al, (2018), who reported that, pain persisted longer in patients who were treated with autgenous graft than in patients who was treated with the combined use of PRF and autogenous graft. (16) According to this study, all patients gained uneventful closure of the alveolar arch and no oronasal fistula had been detected at the end of the follow-up (i.e. after 6 months).…”

Section: Discussionmentioning

confidence: 57%

Evaluation of use of platelet rich fibrin combined with autogenous iliac bone graft for closure of unilateral alveolar cleft

Naguib

2018

Egyptian Dental Journal

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Section: Discussionmentioning

confidence: 57%

Evaluation of use of platelet rich fibrin combined with autogenous iliac bone graft for closure of unilateral alveolar cleft

Naguib

2018

Egyptian Dental Journal

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“…Surgical correction of the defects using grafts like iliac crest with or without growth factor and placement of implants was an expensive and time taking procedure for this patient. 6 Some authors suggested alloplast graft with collagen membrane provides good result in cleft alveolus. 7 In this clinical situation, conventional removable prosthesis or fixed prosthesis was not a feasible option.…”

Section: Discussionmentioning

confidence: 99%

“…1 The bar should be at least 2 mm in height for sufficient strength to support the removable portion of restoration. 6 The removable component includes acrylic teeth on acrylic denture base. There are various treatment options to rehabilitate such kind of challenging cases like removable partial denture, cast partial denture, implant placement after bone augmentation etc.…”

Section: Discussionmentioning

confidence: 99%

“…There are various treatment options to rehabilitate such kind of challenging cases like removable partial denture, cast partial denture, implant placement after bone augmentation etc. 6 Removable partial denture and cast partial denture were ruled out because patient refused to use any removable prosthesis as patient was young and having high aesthetic and functional demands. Patient has refused for implant placement because of increased morbidity due to surgical intervention, as presence of huge defect at surgical site may require autogenous graft like iliac crest which is associated with secondary site morbidity, multiple appointments and economical reasons.…”

Section: Discussionmentioning

confidence: 99%

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Andrew's bridge system: A boon for huge ridge defect in aesthetic zone

Soni

Yadav

Kumar

2020

Journal of Oral Biology and Craniofacial Research

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Tooth loss may pose a challenge for prosthetics when several missing teeth are associated with huge vertical and horizontal bone defects due to cleft palate, road traffic accidents, congenital defects etc. This case report presents prosthetic rehabilitation of a 22 year old male patient of cleft lip and palate with missing upper front teeth along with severe ridge defect since 1 year due to surgical intervention in premaxillary region. The extensive soft and hard tissue defect in aesthetic region was evident and it made the prosthetic rehabilitation more challenging. Among treatment options, fixed partial denture (FPD) was not feasible due to long edentulous span and extensive soft and hard tissue loss. Psychologically, patient was not ready for removable prosthesis. Patient was also not ready for next implant or bone augmentation surgery procedure. The patient presented with Kennedy class IV edentulous area with Seibert's class III ridge defect, so fixed-removable prosthesis was planned to compensate soft and hard tissue defect. The patient with several missing teeth and extensive visible bony defect in the anterior region was successfully rehabilitated using fixed-removable Andrew's bridge system. Although it is not commonly used by dentist so this present case report shows effective management of huge defect case by very simple and conservative technique.

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“…Alveolar clefts are congenital bone defects in the alveolar bone that affect 75% of cleft lip or cleft lip and palate patients (114). The combination of iliac graft and PRP reduce bone resorption compared to iliac graft alone in patients requiring alveolar cleft augmentation (95, 96). On the other hand, adding PRF to iliac bone grafts, did not benefit maxillary alveolar bone thickness, height, and density or the percentage of newly formed bone (97, 98).…”

Section: Regenerative Properties Of Platelet Granulesmentioning

confidence: 99%

Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration

Al-Hamed

Mahri

Al-Waeli

et al. 2019

Front. Cardiovasc. Med.

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Platelet concentrates (PCs) are biological autologous products derived from the patient's whole blood and consist mainly of supraphysiologic concentration of platelets and growth factors (GFs). These GFs have anti-inflammatory and healing enhancing properties. Overall, PCs seem to enhance bone and soft tissue healing in alveolar ridge augmentation, periodontal surgery, socket preservation, implant surgery, endodontic regeneration, sinus augmentation, bisphosphonate related osteonecrosis of the jaw (BRONJ), osteoradionecrosis, closure of oroantral communication (OAC), and oral ulcers. On the other hand, no effect was reported for gingival recession and guided tissue regeneration (GTR) procedures. Also, PCs could reduce pain and inflammatory complications in temporomandibular disorders (TMDs), oral ulcers, and extraction sockets. However, these effects have been clinically inconsistent across the literature. Differences in study designs and types of PCs used with variable concentration of platelets, GFs, and leucocytes, as well as different application forms and techniques could explain these contradictory results. This study aims to review the clinical applications of PCs in oral and craniofacial tissue regeneration and the role of their molecular components in tissue healing.

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Alveolar bone graft with Platelet Rich Plasma in cleft alveolus

Abstract: We conclude that on preliminary investigations, PRP seems to enhance bone formation in alveolar clefts when admixed with autologous cancellous bone harvested from the iliac crest.

Cited by 26 publications

References 14 publications

Evaluation of use of platelet rich fibrin combined with autogenous iliac bone graft for closure of unilateral alveolar cleft

Evaluation of use of platelet rich fibrin combined with autogenous iliac bone graft for closure of unilateral alveolar cleft

Andrew's bridge system: A boon for huge ridge defect in aesthetic zone

Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration

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