Alveolar Adenoma Resected by Thoracoscopic Surgery

Wang, Luming; Wang, Xiaoling; Rustam, Azmat; Hu, Jian

doi:10.5761/atcs.cr.13-00118

Cited by 11 publications

(16 citation statements)

References 5 publications

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“…Most of the tumors remain stable in size over a long period of time, although a few cases have shown an increase in size in the short term. 6,7 Common methods, such as chest CT, electronic fiber bronchoscopy, sputum examination, and other detection methods have not been useful for identifying the disease. Unfortunately, percutaneous biopsy may pose a potential danger because it is difficult to avoid malignant transfer by the needle.…”

Section: Discussionmentioning

confidence: 99%

Alveolar adenoma with poor imaging: a case report

Yuan

Huang

et al. 2019

J Int Med Res

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Alveolar adenoma is an isolated, well-defined peripheral lung tumor that originates from type II alveolar cells. The tumor consists of a network of simple, low-cubic, epithelium-coated lacunae with varying amounts of fine and inconspicuous-to-thick spindle cells that sometimes contain mucus sample matrix. Few cases of alveolar adenoma have been reported. These tumors are usually detected by imaging examinations where the alveolar adenoma typically presents as a peripheral, solitary cystic nodule in the lung. The presentation may mimic that of other types of lung tumors, consequently leading to difficulties in the differential diagnosis of this condition. Thus, accurate diagnosis of alveolar adenoma is based on a combination of pathological sections and immunohistochemistry. This study describes an alveolar adenoma in a 59-year-old female patient. Chest X-ray imaging and chest computed tomography identified malignant lesions in the right upper lobe. The patient subsequently underwent a thoracoscopic right upper lobectomy. The diagnosis of alveolar adenoma was confirmed after pathological examination of the excised postoperative tissue. The disease course was stable, and there was no recurrence of pulmonary lesions during 3 years of postoperative patient follow-up. Herein, we report the case of a patient with benign alveolar adenoma with poor imaging and pathological results.

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Section: Discussionmentioning

confidence: 99%

Alveolar adenoma with poor imaging: a case report

Yuan

Huang

et al. 2019

J Int Med Res

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“…The presence of TTF-1 expression in AA can help distinguish it from sclerosing pneumocytoma. Pulmonary hamartoma consists primarily of benign cartilage mixed with a fibrovascular stroma and scattered bronchial glands ( 9 ).…”

Section: Discussionmentioning

confidence: 99%

Alveolar adenoma with a single cyst: A case report

Matsui,

Utsumi,

Maru

et al. 2024

Med Int

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Alveolar adenoma is a rare and benign pulmonary tumor, which originates from type II pneumocytes and is often incidentally identified on radiographic images. Alveolar adenoma presents as a peripleural, solitary and cystic nodule in the lung and may mimic other types of lung tumors, thus rendering its differential diagnosis difficult. Alveolar adenoma is diagnosed based on histopathological and immunohistochemical analyses. The present study describes the case of a 50-year-old male patient with alveolar adenoma. He visited a local doctor ~3 years prior due to left chest pain. A chest computed tomography scan revealed a cystic lesion in segment 8 of the left lung. A nodular shadow appeared in the cyst and gradually increased in size; the patient was thus referred to the authors' hospital. The nodule was well-defined, solitary and solid; thus, lung cancer or aspergilloma were suspected. Thoracoscopic wedge resection was performed as diagnostic therapy. The frozen sections were non-diagnostic, and a pathological examination revealed an alveolar adenoma with no evidence of malignancy and a negative culture. The patient had a good post-operative course, with no sign of recurrence at the follow-up evaluation 46 months later. On the whole, alveolar adenoma is a rare, benign pulmonary tumor that is difficult to diagnose pre-operatively.

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“…There are a few case reports that describe multiple lesions detected on imaging, although pathologic confirmation was obtained for only a single lesion in each case with the presumption that the additional lesions represented the same pathological entity (4). This lesion is predominantly found in middleaged women and typically demonstrates a peripheral and subpleural location, however more central locations have occasionally been described (5,6). Although alveolar adenomas are generally regarded as benign, there is a single case report describing the malignant transformation of an alveolar adenoma into an adenocarcinoma in an elderly patient (7).…”

Section: Discussionmentioning

confidence: 99%