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Raizer, Jeffrey J.; Shetty, Teena; Gutin, Philip H.; Obbens, Eugenie A.M.T.; Holodny, Andrei I.; Antonescu, Cristina R.; Rosenblum, Marc K.

doi:10.1023/a:1023752717042

Cited by 41 publications

(5 citation statements)

References 13 publications

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“…The most common surgical approaches described to resect CG include transcallosal in 7 [12, 29, 37, 43, 44, 50], transcortical in 5 [22, 31, 51, 52], and trans-lamina terminalis in 17 [4, 11, 13, 17, 20, 23, 42, 43, 46, 47, 53–55]. Surgical approach was not specified in 52 patients.…”

Section: Resultsmentioning

confidence: 99%

“…In particular, one of these patients continues to have severe amnesia at last follow up of 40 months. [43] Non-neurologic complications including hematoma formation [6, 31, 47] and bacterial meningitis [4, 50] were also reported. There were 5 reported cases of pulmonary embolism (6.3%).…”

Section: Resultsmentioning

confidence: 99%

“…For those patients who did have progression, specifically within the STR group, time to progression ranged from 4 months to 4 years. The limited follow up for select patients undergoing GTR[7, 13, 14, 21, 38, 39, 41, 50, 53] may have precluded detection of later recurrences.…”

Section: Discussionmentioning

confidence: 99%

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Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature

Ampie

Choy

Lamano

et al. 2015

Clinical Neurology and Neurosurgery

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Introduction Chordoid Gliomas (CG) are rare neoplasms which frequently arise within the third ventricle. Surgery remains the mainstay treatment for CG. The present study comprehensively reviews all reported cases of CG within the literature in order to identify risk factors for surgical complications and tumor recurrence. Methods A comprehensive search on MEDLINE (OVID and Pubmed), Scopus, Embase, and Web of Science was conducted following PRISMA guidelines to identify all reported cases of CG. Results A total of 81 patients met the study criteria, comprised of 33 males and 48 females. Median age at diagnosis was 48 years with a range from 5 to 72 years, and mean tumor size was 3.1 cm. Biopsy, subtotal resection (STR), and gross total resection (GTR) was achieved in 8, 34, and 33 patients, respectively, with 6 cases not reporting extent of eresection (EOR). Thirteen patients underwent adjuvant radiotherapy. Postoperative complications were noted in 30 cases (37%), with new onset diabetes insipidus being the most common. Postoperative morbidity was not associated with age, tumor size, or extent of resection. A trans-lamina terminalis approach demonstrated a strong trend towards decreased overall rates of postoperative morbidity compared to other approaches (p=0.051). GTR was associated with improved progression-free survival (PFS; p=0.028), while adjuvant radiotherapy, age, tumor size and MIB-I were not predictive of patient outcomes. Conclusion GTR should be the primary goal for the management of CG, as it is associated with improved rates of tumor control without an increased rate of postoperative complications. Surgical approach was a stronger predictor of complication rates than extent of resection. Morbidity remains high, and future studies to further elaborate on factors predictive of postoperative complications are critical.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature

Ampie

Choy

Lamano

et al. 2015

Clinical Neurology and Neurosurgery

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“…Our patient was unable to assess the clinical changes caused by hyponatremia due to changes in the state of consciousness. Symptoms caused by neuroendocrine dysfunction may be relatively rare in CGs; a few cases with amenorrhea, hypothyroidism, diabetes insipidus and SIADH have been reported (Brat et al, 1998 ; Raizer et al, 2003 ; Kurian et al, 2005 ; Dziurzynski et al, 2009 ; Ni et al, 2013 ; Edate and Albanese, 2015 ; Calanchini et al, 2016 ; Cuesta et al, 2016 ; Danilowicz et al, 2018 ) ( Supplementary Table 3 ). Central diabetes insipidus, SIADH and cerebral salt wasting syndrome are the main reasons for craniocerebral surgery in the treatment of sodium metabolism imbalance.…”

Section: Discussionmentioning

confidence: 99%

Occurrence of Chordoid Glioma With Sodium Ion Metabolism Disorder 5 Years After Meningioma Surgery and Whole-Exome Sequencing: A Case Report and Literature Review

Zhang

et al. 2021

Front. Genet.

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Chordoid glioma (CG), a rare slow-growing brain tumor, mainly occurs in the region of the third ventricle. Although its degree of malignancy is relatively low, its clinical prognosis is poor due to obscure clinical manifestations and the particular growing position. Currently, gross total resection is the best available method for treatment of CG. However, the tumor is located in the deep structure of the brain and close to neurovascular structure so it is difficult to remove completely. This study reported a case of CG of the third ventricle 5 years after surgery of right frontal parietal fibrous meningioma, accompanied with peri and post-operative sodium ion metabolism disorder. Whole-exome sequencing (WES) revealed 25 gene mutations shared by meningioma and CG. In addition, the PRKCAD463H CG marker gene mutation also existed in this patient. We reviewed the latest literature on this rare brain tumor, summarized its clinical manifestations, imaging and pathological characteristics, and discussed the mechanism related to its occurrence and the reasons for sodium ion disorder.

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“…[ 2 3 9 12 13 14 19 20 ] In previous reports, chordoid glioma has been described as tending to occur in middle-aged and older adults (25–75 years). [ 8 15 ] The clinical symptoms of this tumor are variable, according to tumor size and location. [ 3 4 9 12 18 19 ] However, the epidemiology has not been clarified because of the low incidence of this tumor.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of neuroimaging and immunohistochemical study for accurate diagnosis of chordoid glioma of the third ventricle: A case report and review of the literature

Shinohara¹,

Inoue²,

Kohno³

et al. 2018

Surg Neurol Int

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Background:Chordoid glioma of the third ventricle is a rare neuroepithelial tumor characterized by a unique histomorphology within the third ventricular region, but with radiological and histopathological features mimicking benign lesions such as meningioma. We report a case of chordoid glioma of the third ventricle and suggest a useful indicator for accurate diagnosis.Case Description:A previously healthy 46-year-old woman was admitted to our hospital with mild headache. Neuroimaging revealed a large tumor measuring approximately 18 mm in the suprasellar region, and perifocal edema in the optic tract and internal capsule on magnetic resonance imaging. Laboratory findings revealed no pituitary dysfunction including diabetes insipidus. Gross total resection of the tumor was performed by the interhemispheric translamina terminalis approach. Histological findings revealed nests of regular epithelioid cells with large nuclei and abundant eosinophilic cytoplasm within myxoid stroma. Immunohistochemical studies demonstrated diffuse cytoplasmic expression of glial fibrillary acidic protein (GFAP) and CD34, and strong nuclear staining for thyroid transcription factor 1 (TTF-1). We, therefore, histologically classified the tumor as chordoid glioma of the third ventricle. Headache improved immediately postoperatively, and follow-up neuroimaging after 12 months showed no signs of recurrence.Conclusions:Chordoid glioma of the third ventricle is a very rare tumor that is difficult to diagnose on routine neuroimaging. Accurate diagnosis requires detailed analysis of neuroimaging and immunohistochemical studies using CD34 and TTF-1 staining.

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Cited by 41 publications

References 13 publications

Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature

Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature

Occurrence of Chordoid Glioma With Sodium Ion Metabolism Disorder 5 Years After Meningioma Surgery and Whole-Exome Sequencing: A Case Report and Literature Review

Usefulness of neuroimaging and immunohistochemical study for accurate diagnosis of chordoid glioma of the third ventricle: A case report and review of the literature

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