Aluminosilicates and biphasic HA-TCP composites: studies of properties for bony filling

Abstract

Aluminosilicate materials synthesized at room temperature present good mechanical properties. Hydroxyapatite, tricalcium phosphate or both offer a high biocompatibility in the biomedical field. In this work, we focused on the composites resulting from associations of these materials. The best compromise between porosity and biomechanical properties versus different parameters was determined. The in vitro behaviour of compounds in contact with the simulated body fluid (SBF) was studied and in vivo experiments in a rabbit's thighbones were carried out. The inductively coupled plasma-optical emission spectroscopy (ICP-OES) method permitted us to study the eventual release of Al from composites to SBF and to evaluate the chemical stability of composites characterized by the succession of SiO(4) and AlO(4) tetrahedra. The kinetic biomineralization, the bioconsolidation and biological studies were made. The results obtained show the chemical stability of composites. In the bone-implant interface, the intimate links reveal the high quality of the biointegration and the bioconsolidation between composites and bony matrix. Histological studies confirm good bony bonding and highlight the total absence of inflammation or fibrous tissues.

Doping and calcination effect on nanostructured aluminosilicates processed by sol-gel route

“…Aluminosilicate systems synthesised at room temperature by sol-gel route present attractive properties for medical application as biomaterials [1][2][3], but also as catalysts [4,5]. In addition to chemical composition, the structure, surface topographical features and the nanoscale changes in surface layer all have significant effects on their bioactive and catalytic properties [4][5][6].…”

Synthesis of crystalline and amorphous, particle-agglomerated 3-D nanostructures of Al and Si oxides by femtosecond laser and the prediction of these particle sizes

“…Aluminosilicate ceramic is a biomedical material that has shown biocompatibility in simulated body fluid. It is applied in bone filling, protein absorption, and nanobiocomposites [7][8][9][10]. The sol-gel dry spinning [11] technique has been extensively used for the fabrication of highly pure, homogeneous, crack-free aluminosilicate ceramic microfibers at low temperature.…”

Inorganic Polymers (Geopolymers) as Potential Bioactive Materials

“…reported that they successfully made materials which were accepted by host bone and provided good mechanical properties. Further, neither inflammation or encapsulation of the surrounding tissue occurred nor leaching out of harmful elements from the sample was recorded [3].…”

“…Geopolymers are presently used for a variety of applications including heat resistant materials and fire protection. Specialist geopolymers have been developed as biomaterials to replace/ repair damaged animal bones [3] [4].…”