Aluminium in infant foods: Total content, effect of in vitro digestion on bioaccessible fraction and preliminary exposure assessment

Paiva, Esther Lima de; Medeiros, Camila; Fioravanti, Maria Isabel Andrekowisk; Milani, Raquel Fernanda; Morgano, Marcelo Antônio; Pallone, Juliana Azevedo Lima; Arisseto-Bragotto, Adriana Pavesi

doi:10.1016/j.jfca.2020.103493

Cited by 7 publications

(6 citation statements)

References 42 publications

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“…The highest levels (0.4 mg/kg) were in the first brand in all its samples. The levels of Al in pureed foods in our study were comparable to those reported in a study in France (0.189 to 0.653 mg/kg) [ 23 ], but lower than those in Ghana (2.89 to 11.07 mg/kg) [ 24 ] and Brazil (0.21 to 4.17 mg/kg) [ 25 ]. The levels of Al in infant cereals (0.3 mg/kg) in our study were lower than those reported in a study in Brazil (0.92 to 8.82 mg/kg) [ 25 ].…”

Section: Discussionsupporting

confidence: 86%

“…The levels of Al in pureed foods in our study were comparable to those reported in a study in France (0.189 to 0.653 mg/kg) [ 23 ], but lower than those in Ghana (2.89 to 11.07 mg/kg) [ 24 ] and Brazil (0.21 to 4.17 mg/kg) [ 25 ]. The levels of Al in infant cereals (0.3 mg/kg) in our study were lower than those reported in a study in Brazil (0.92 to 8.82 mg/kg) [ 25 ]. Moreover, our data show that the Al levels in cornflake samples were the highest (0.4 mg/kg), yet there is no study in the literature in which cornflake Al levels are described.…”

Section: Discussionsupporting

confidence: 86%

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Pediatric Health Risk Assessment for Exposure to Aluminum from Infant Formulas and Children under the Age of Five’s Food Products among Arab Infants: Experience from Lebanon

Ibrahim

Kamouni

Barake

et al. 2022

Foods

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Chronic dietary aluminum (Al) exposure can have various negative effects on health. The aim of our study is to (1) assess the contamination level of Al in infant formulas (n = 41) and baby food products (n = 76) available in the Lebanese market, and to (2) evaluate the margin of exposure of Al through the consumption of these foods among children under the age of five in Lebanon. Flame atomic absorption spectrometry (FAAS) was used to evaluate all of the samples. Al levels in all tested children’s food items were below the limit of detection. The highest Al level was detected in cornflakes (0.361 ± 0.049 mg/kg) and pureed foods (0.362 ± 0.079 mg/kg). Among infants aged 0–23 months, the average Al exposure due to the daily intake of infant formulas and baby foods was 0.01 and 0.0104 mg/kg BW/day for males and females, respectively. Babies aged 8–10 and 3–5 months had the highest and lowest levels of Al exposure, respectively. Additionally, the toxicological contribution of Al exposure determined for several age groups to a provisional tolerated weekly intake (PTWI) set by JECFA was <6% and <7% for males and females, respectively. The total Al exposure through the consumption of infant formulas and complementary foods among all ages in both males and females was below the values of weekly tolerable intakes (2 mg/kg/BW/W) set by JECFA. However, the values of hazard quotient (HQ) exceeded 1 in both male and female Lebanese infants. As a result, the risk of infants being exposed to Al in baby foods needs to be continuously considered.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 86%

Pediatric Health Risk Assessment for Exposure to Aluminum from Infant Formulas and Children under the Age of Five’s Food Products among Arab Infants: Experience from Lebanon

Ibrahim

Kamouni

Barake

et al. 2022

Foods

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“…Nowadays, its aluminum derivatives are used in water‐treatment, food additives, processed cheese. Also, Al 3+ has been detected in herbal tea samples, [2] milk, [3] vaccines, [4] infant food, [5] and cocoa [6] . Aluminum can be toxic to bone, [7] some neurological effects have been observed, [8] and cause dialysis encephalopathy [9] .…”

Section: Introductionmentioning

confidence: 99%

Schiff Bases and Multidentate Organic Compounds as Fluorescent Sensors of Al³⁺: Photophysical, Fluorescent Bioimaging and the Mechanisms

et al. 2022

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“…These heavy metals cause damage to various organs after leaving the systemic circulation. However, the great problem associated with these elements is their accumulation over time in various organs and the damage generated by mechanisms such as the breakdown of enzymes, hormones, proteins, and cell membranes, among others, as they have no biological function [ 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. There are also reports of long-term human exposure to low levels of barium (Ba), which is associated with symptoms of diarrhea, cardiac arrhythmia, muscle weakness, anxiety, and nervous system disorders [ 19 , 20 ]; thus, it requires evaluation since its presence is widespread in the environment [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

Rebellato¹,

Fioravanti

Milani³

et al. 2023

IJERPH

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This study aimed to evaluate the content of 11 inorganic elements (Al, Cr, Co, Ni, As, Mo, Cd, Sb, Ba, Hg, and Pb) in commercial plant-based and animal-based yogurts for comparison purposes. The samples were mineralized using a simple and fast ultrasound-assisted acid digestion method at 80 °C for 35 min, and the determination of inorganic elements was performed by ICP-MS. The method was validated according to the INMETRO guide, obtaining recoveries from 80 to 110%, precision from 6 to 15%, and a limit of quantification (LOQ) ranging from 200 µg/kg (Al) to 4 µg/kg (other elements). The element concentrations in the plant-based yogurts were Al(<LOQ-9019.05); Cr(<LOQ-88.14); Co(<LOQ-40.56); Ni(31.71-700.46); As(<LOQ-10.61); Mo(<LOQ-355.70); Cd(<LOQ-4.37); Sb and Hg(<LOQ); Ba(<LOQ-1505.71), and Pb(<LOQ-21.58) µg/kg. The elements Mo and Ba were quantified only in the animal-based yogurts, with levels of 72.54 and 160.76 µg/kg, respectively. The results showed a large variation in the concentration of inorganic elements, which demonstrates the importance of knowing the composition of plant-based foods to ensure the safety and health of consumers.

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Aluminium in infant foods: Total content, effect of in vitro digestion on bioaccessible fraction and preliminary exposure assessment

Cited by 7 publications

References 42 publications

Pediatric Health Risk Assessment for Exposure to Aluminum from Infant Formulas and Children under the Age of Five’s Food Products among Arab Infants: Experience from Lebanon

Pediatric Health Risk Assessment for Exposure to Aluminum from Infant Formulas and Children under the Age of Five’s Food Products among Arab Infants: Experience from Lebanon

Schiff Bases and Multidentate Organic Compounds as Fluorescent Sensors of Al³⁺: Photophysical, Fluorescent Bioimaging and the Mechanisms

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

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Aluminium in infant foods: Total content, effect of in vitro digestion on bioaccessible fraction and preliminary exposure assessment

Cited by 7 publications

References 42 publications

Pediatric Health Risk Assessment for Exposure to Aluminum from Infant Formulas and Children under the Age of Five’s Food Products among Arab Infants: Experience from Lebanon

Pediatric Health Risk Assessment for Exposure to Aluminum from Infant Formulas and Children under the Age of Five’s Food Products among Arab Infants: Experience from Lebanon

Schiff Bases and Multidentate Organic Compounds as Fluorescent Sensors of Al3+: Photophysical, Fluorescent Bioimaging and the Mechanisms

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

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Product

Resources

About

Schiff Bases and Multidentate Organic Compounds as Fluorescent Sensors of Al³⁺: Photophysical, Fluorescent Bioimaging and the Mechanisms