Alternative treatment of recurrent Clostridioides difficile infection in adults by fecal transplantation: an overview of phase I–IV studies from Clinicaltrials.gov
Najla A. Obaid
Abstract:BackgroundFecal microbiota transplantation (FMT) is an interventional approach to treat chronic and recurrent Clostridioides difficile infection (CDI). However, there is insufficient evidence regarding its effectiveness and safety. Clinical trials have been conducted to inspect the safety and effectiveness of FMT with and without comparison to pharmacological treatments.AimThis review explored the treatment of CDI in adults using FMT and evaluated the safety of this intervention based on phase I–IV studies reg… Show more
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