Alternative strategies in the treatment of bronchial asthma

Veen, J. C. C. M. In't; Sterk, Peter J.; Bel, Elisabeth H.

doi:10.1046/j.1365-2222.2000.00719.x

Clin Experimental Allergy

2000

DOI: 10.1046/j.1365-2222.2000.00719.x

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Alternative strategies in the treatment of bronchial asthma

J. C. C. M. In't Veen

Peter J. Sterk

Elisabeth H. Bel

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Cited by 3 publications

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References 265 publications

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“…In another extensive review of alternative strategies in the treatment of asthma, the authors expressed skepticism about the value of CAM in the treatment of asthma. 10 Most of the therapies included in that review were medically based, but were only considered alternative in that the therapies were not considered conventional asthma treatment. Studies involving CAM therapies were limited, and studies of HPs were not included in the review.…”

mentioning

confidence: 99%

Herbals and Asthma: Usage Patterns Among a Border Population

Rivera

Hughes

Stuart³

2004

Ann Pharmacother

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mentioning

confidence: 99%

Herbals and Asthma: Usage Patterns Among a Border Population

Rivera

Hughes

Stuart³

2004

Ann Pharmacother

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2000

Alternative and Complementary Therapies

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Oral tolerance attenuates changes in in vitro lung tissue mechanics and extracellular matrix remodeling induced by chronic allergic inflammation in guinea pigs

Nakashima

Prado²,

Lanças³

et al. 2008

Journal of Applied Physiology

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Recent studies emphasize the presence of alveolar tissue inflammation in asthma. Immunotherapy has been considered a possible therapeutic strategy for asthma, and its effect on lung tissue had not been previously investigated. Measurements of lung tissue resistance and elastance were obtained before and after both ovalbumin and acetylcholine challenges. Using morphometry, we assessed eosinophil and smooth muscle cell density, as well as collagen and elastic fiber content, in lung tissue from guinea pigs with chronic pulmonary allergic inflammation. Animals received seven inhalations of ovalbumin (1-5 mg/ml; OVA group) or saline (SAL group) during 4 wk. Oral tolerance (OT) was induced by offering ad libitum ovalbumin 2% in sterile drinking water starting with the 1st inhalation (OT1 group) or after the 4th (OT2 group). The ovalbumin-exposed animals presented an increase in baseline and in postchallenge resistance and elastance related to baseline, eosinophil density, and collagen and elastic fiber content in lung tissue compared with controls. Baseline and post-ovalbumin and acetylcholine elastance and resistance, eosinophil density, and collagen and elastic fiber content were attenuated in OT1 and OT2 groups compared with the OVA group. Our results show that inducing oral tolerance attenuates lung tissue mechanics, as well as eosinophilic inflammation and extracellular matrix remodeling induced by chronic inflammation.

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Alternative strategies in the treatment of bronchial asthma

Cited by 3 publications

References 265 publications

Herbals and Asthma: Usage Patterns Among a Border Population

Herbals and Asthma: Usage Patterns Among a Border Population

LiteratureWatch

Oral tolerance attenuates changes in in vitro lung tissue mechanics and extracellular matrix remodeling induced by chronic allergic inflammation in guinea pigs

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