Abstract:Genome sequencing is the process by which the sequence of deoxyribonucleic acid (DNA) residues that compromise the genome, or complete set of genetic materials of an organism or individual, is determined. Down-stream analysis of genome sequencing data requires that short reads be compiled into contiguous sequences. These methods, called de novo assembly, are based in statistical methods and graph theory. In addition to genome assembly, the research presented in this dissertation demonstrates the alternative us… Show more
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