2015
DOI: 10.1016/j.neulet.2015.03.002
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Altered serum glyceraldehyde-derived advanced glycation end product (AGE) and soluble AGE receptor levels indicate carbonyl stress in patients with schizophrenia

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Cited by 22 publications
(35 citation statements)
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“…Psychotic patients in general are in a significantly increased longterm con dition of oxidative stress [102,103] . Oxidative stress markers, such as pentosidine [104] , glycer-AGE [105] and thiobarbituric acid reactive substances [103,106] were found to be higher among people with Sz and carbonyl stress was found to be lower in people with the disorder [104,105,107] . However, those oxidative markers have overlapping levels between people with Sz and healthy individuals, suggesting the discriminability of those markers is low [102] .…”
Section: Metabolismmentioning
confidence: 90%
“…Psychotic patients in general are in a significantly increased longterm con dition of oxidative stress [102,103] . Oxidative stress markers, such as pentosidine [104] , glycer-AGE [105] and thiobarbituric acid reactive substances [103,106] were found to be higher among people with Sz and carbonyl stress was found to be lower in people with the disorder [104,105,107] . However, those oxidative markers have overlapping levels between people with Sz and healthy individuals, suggesting the discriminability of those markers is low [102] .…”
Section: Metabolismmentioning
confidence: 90%
“…Converging evidence indicates that the OS plays a role in SCZ pathophysiology [46][47][48][49]. A study on the disturbances in antioxidative defense systems indicated an increase in free radical generation and antioxidant defense impairment in SCZ patients [46].…”
Section: Oxidative Stress-a Field For New Tailored Therapies?mentioning
confidence: 99%
“…Accumulation of these products is called carbonyl stress, and has been suggested as an environmental factor in the pathophysiology of SCZ [47,49,53]. AGEs interact with AGE receptors (RAGE) on the cell membrane, which induces deleterious effects by increasing oxidative and carbonyl stress [49,54].…”
Section: Oxidative Stress-a Field For New Tailored Therapies?mentioning
confidence: 99%
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