Altered pupil light and darkness reflex and eye-blink responses in late-life depression
Yao-Tung Lee,
Yi-Hsuan Chang,
Hsu-Jung Tsai
et al.
Abstract:Background
Late-life depression (LLD) is a prevalent neuropsychiatric disorder in the older population. While LLD exhibits high mortality rates, depressive symptoms in older adults are often masked by physical health conditions. In younger adults, depression is associated with deficits in pupil light reflex and eye blink rate, suggesting the potential use of these responses as biomarkers for LLD.
Methods
We conducted a study using video-based eye-t… Show more
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