“…For the present analyses life-time (past or present) diagnoses of the 18 single mental disorders (Figure 1A and Supplemental Table S1) used in our analyses were determined. Based on the definitions of broad diagnostic families in recent studies (13, 16, 29), three broad diagnostic families in our analyses (Figure 1A) were determined as externalizing disorders (Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder), internalizing disorders (Dysthymia, Major Depressive Disorder, Disruptive Mood Dysregulation Disorder, Agoraphobia, Panic Disorder, Specific Phobia, Separation Anxiety Disorder, Social Anxiety Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder), thought disorders (Hallucinations, Delusions, Associated Psychotic Symptoms, Bipolar Disorder, Obsessive-Compulsive Disorder). As expected there was a high comorbidity among the three broad diagnostic families (Figure 1B and Table 1).…”