Altered intratumoral immune composition after Nivolumab treatment in patients with recurrent glioblastoma
Sine Hadrup,
Signe Skadborg,
Simone Maarup
et al.
Abstract:Glioblastoma is an aggressive brain tumor with poor prognosis, and consequently immunotherapy is being explored as a potential treatment option. However, it is unclear whether systemic immunotherapy can reach and modify the tumor microenvironment in the brain. We evaluated immune characteristics in tumor and blood samples from recurrent glioblastoma patients, who received Nivolumab and Bevacizumab. One group received Nivolumab one week prior to surgery, and immune characteristics of the tumor were compared to … Show more
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