“…Thus, this decrease in the anatomical connections between either left caudate or right midcingulate cortex and other regions of the brain would be expected to isolate these two regions and could explain the loss of these two nodes as connector hubs. Caudate is associated with different aspects of cognition, including motor and action planning, decision‐making (particularly, goal‐directed behavior), motivation and reward processing (Bick et al., 2019; Cera et al, 2019; Grahn et al., 2008; Wilson, 2018). Previous studies exploring age‐related changes in the caudate have shown associations with different cognitive domains, such as episodic memory (Fjell, Sneve, Storsve, et al., 2016; Rieckmann et al., 2018), instrumental learning (Perosa et al., 2020), cognitive flexibility (Verstynen et al., 2012), and reward processing (Bowen et al., 2020; Dhingra et al., 2020).…”