“…Indeed, the cerebellum has been shown to be involved in the pathology of depression by converging evidence. In addition to the structural abnormalities of the cerebellum observed in depression (Allen et al, 1997;Frodl et al, 2010;Lee et al, 2011;Liu et al, 2010;Peng et al, 2011;Soares and Mann, 1997), several functional MRI studies have found irregular activation patterns in the cerebellum, for instance, altered cerebellar-cerebral functional connectivity during the resting state (Alalade et al, 2011;Liu et al, 2012;Zeng et al, 2012) and abnormal cerebellum activation in MDD patients performing cognitive (Chantiluke et al, 2012) and emotional tasks (Fitzgerald et al, 2008;Frodl et al, 2010). Moreover, despite an early, intense dispute, the significant insight that the cerebellum not only subserves the prevailing motor coordination but also some other higher functions, i.e., cognition and emotion control, has achieved strong consensus (Allen et al, 1997;Gao et al, 1996;Konarski et al, 2005;Middleton and Strick, 1994).…”