“…Regarding transcriptomics, previous studies explored blood gene expression in patients with AD with the objective of finding a common signature that could help identifying those individuals at risk of AD. A differential expression profile has been observed not only when comparing AD to controls [[59], [60], [61], [62], [63], [64], [65], [66]], or MCI to controls [64], but also when comparing rapidly progressing AD patients to slowly progressing patients [67], and patients with AD to patients with vascular dementia [61]. Those differentially expressed genes were grouped according to biological functions such as inflammation [60,68,69], immune response [61,65], cell cycle and apoptosis [61,65,68,69], gene expression [65,68], cytoskeleton [59,65], and interaction with the extracellular matrix [59,70].…”