1993
DOI: 10.1016/0378-4274(93)90074-8
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Altered behaviour in adult mice orally exposed to tri- and tetrachloroethylene as neonates

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Cited by 25 publications
(31 citation statements)
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“…Because control levels of activity generally fell sharply over the 60-min test, control values for the last 20-min test interval are often not possible to read from the originally published bar graphs; therefore, only data for the first 20-min test interval are shown here. In order to limit experimental variability, the data shown are from studies of compounds that were administered orally in the egg lecithinpeanut oil emulsion vehicle to male NMRI mice on, or starting on, PND10 (Talts et al, 1998;Johansson et al, 1995;Fischer et al, 2008aFischer et al, , 2008bFredriksson et al, 1993aFredriksson et al, , 1993bAhlbom et al, 1994Ahlbom et al, , 1995Eriksson et al, 1990aEriksson et al, , 1990bEriksson et al, , 1992Eriksson et al, , 1993Eriksson et al, , 2001Eriksson et al, , 2002Eriksson et al, , 2006aEriksson et al, , 2006b, 1996Viberg et al, 2002Viberg et al, , 2003aViberg et al, , 2003bViberg et al, , 2006. Data from studies using other species or strains, other routes of exposure, other days of treatment, and other administration vehicles have been excluded from this analysis in order to minimize potential sources of inconsistency.…”
Section: Test Apparatus and Methodologymentioning
confidence: 99%
“…Because control levels of activity generally fell sharply over the 60-min test, control values for the last 20-min test interval are often not possible to read from the originally published bar graphs; therefore, only data for the first 20-min test interval are shown here. In order to limit experimental variability, the data shown are from studies of compounds that were administered orally in the egg lecithinpeanut oil emulsion vehicle to male NMRI mice on, or starting on, PND10 (Talts et al, 1998;Johansson et al, 1995;Fischer et al, 2008aFischer et al, , 2008bFredriksson et al, 1993aFredriksson et al, , 1993bAhlbom et al, 1994Ahlbom et al, , 1995Eriksson et al, 1990aEriksson et al, , 1990bEriksson et al, , 1992Eriksson et al, , 1993Eriksson et al, , 2001Eriksson et al, , 2002Eriksson et al, , 2006aEriksson et al, , 2006b, 1996Viberg et al, 2002Viberg et al, , 2003aViberg et al, , 2003bViberg et al, , 2006. Data from studies using other species or strains, other routes of exposure, other days of treatment, and other administration vehicles have been excluded from this analysis in order to minimize potential sources of inconsistency.…”
Section: Test Apparatus and Methodologymentioning
confidence: 99%
“…However, the direction of effect varied. Exposures to halogenated organic compounds ammonium perfluorooctanoate, potassium perfluorooctane sulfonate, and brominated diethyl ethers 992 and 209 (BDE 992, BDE 209) (Eriksson et al, 1999, 2002; Johansson et al, 2008; Viberg et al, 2003, 2001) were associated with decreased or non-significant changes in motor activity levels, while exposure to tetrachloroethylene and DDT was associated with elevated motor activity (Eriksson et al, 1990a, 1990b; Fredriksson et al, 1993; Johansson et al, 1995, 1996). The NOAEL associated with the halogenated organic compounds derived from post-natal exposures occurring outside our derived window, with the exception of BDE 209 exposure to the highest dose (20.1 mg/kg/day versus 2.22 mg/kg/day) at PND 10 (Viberg et al, 2003, 2001).…”
Section: Review Of Toxicological Profilesmentioning
confidence: 99%
“…For rodents exposed to perc after birth, one study of mice showed no neurobehavioral effects immediately after exposure ceased at PD17, but the mice exhibited increased locomotion and total activity and decreased rearing at PD 60 (Fredriksson et al, 1993).…”
Section: Postnatal Outcomesmentioning
confidence: 99%