Alterations of Ocular Motility in down Syndrome

Becerril-Carmona, Adriana Fabiola; Arroyo-Yllanes, María Estela; Paciuc-Beja, Miguel

doi:10.1080/0065955x.1997.11982134

Cited by 5 publications

(3 citation statements)

References 16 publications

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“…East Asians are known to have myopia, as well as the progression of myopia 30. Previous studies have reported that high myopia is one of the characteristics in subjects with DS 2,5,7,10,11,18,22. In the present study, we found that hyperopia was nearly constant in subjects under 7 years of age, and myopia began to increase in subjects over 7 years of age.…”

Section: Discussionsupporting

confidence: 65%

“… 30 Previous studies have reported that high myopia is one of the characteristics in subjects with DS. 2 , 5 , 7 , 10 , 11 , 18 , 22 In the present study, we found that hyperopia was nearly constant in subjects under 7 years of age, and myopia began to increase in subjects over 7 years of age. Astigmatism was 71.0%~84.8% in the children aged under 10 years, and over 90% in subjects in their late teens, that is, higher than that in the previous reports.…”

Section: Discussionsupporting

confidence: 56%

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Ocular findings in Japanese children with Down syndrome: the course of visual acuity and refraction, and systemic and ocular anomalies

Terai

Eda

Sugasawa

et al. 2018

OPTH

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PurposeTo investigate the age-related development of refractive errors and changes of visual acuity (VA), and the systemic and ocular anomalies in Japanese children and young adults with Down syndrome (DS).DesignRetrospective cohort study.Subjects and methodsThis study involved 222 Japanese children and young adults with DS (age range: 3 months to 19 years) seen at the Department of Ophthalmology, Shiga Medical Center for Children, Shiga, Japan. The subjects were divided into the following six age groups: 1) infant (age 0 to <4 years), 2) preschool (age 4 to <7 years), 3) lower primary-school grades (age 7 to <10 years), 4) upper primary-school grades (age 10 to <13 years), 5) junior high school (age 13 to <16 years), and 6) late teen/young adults (age 16 to <20 years). Through examination of the subjects’ medical charts, we investigated the development and changes of refractive errors and VA, best-corrected VA (BCVA), and systemic and ocular anomalies.ResultsFor vision testing, Teller Acuity Cards™ (Bernell Corporation) were used for the infants, and the Landolt ring was used for the school-age children. VA was found to develop with age. Mean BCVA was 0.19±0.17 logarithm of the minimum angle of resolution (mean age: 11.3±3.2 years). Mean of refractive errors was hyperopia in the infant (2.2±2.4 diopters [D] OD, 2.4±2.5D OS), yet became myopia to the junior high school (−0.3±4.4D OD, −0.2±4.4D OS).ConclusionOur findings revealed that in children and in late-teen and young-adult subjects with DS, VA slowly develops and that refractive errors requiring correction exist and are difficult to examine.

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Section: Discussionsupporting

confidence: 65%

Section: Discussionsupporting

confidence: 56%

Ocular findings in Japanese children with Down syndrome: the course of visual acuity and refraction, and systemic and ocular anomalies

Terai

Eda

Sugasawa

et al. 2018

OPTH

View full text Add to dashboard Cite

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“…5 Infantile esotropia was found in only one patient, divergent from an earlier study that found infantile esotropia in 49.4% of esotropic Down syndrome patients in Mexico. 18 This disparity might be explained by the low prevalence of infantile esotropia in Koreans, 17 as well as by a possible failure to detect esotropia because of epicanthal folds. In this study, esotropia increased with age, but exotropia decreased.…”

Section: Discussionmentioning

confidence: 98%

Refractive errors and strabismus in Asian patients with Down syndrome

2008

Eye

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Purpose The purpose of this study was to investigate the prevalence and patterns of refractive errors and strabismus in Asian patients with Down syndrome, as they relate to age. Methods A total of 261 Korean patients with Down syndrome were examined between March 1999 and May 2007. Eighty-nine patients were excluded from the study. The remaining 172 patients were divided into four age groups (o3 years, 3-o6 years, 6-o9 years, and X9 years). Full ophthalmologic examinations and strabismus assessments were performed. Refractive errors were defined as follows: myopia XÀ1.00 D, hyperopia X þ 1.00 D, astigmatism X±1.00 D, and anisometropia as a refractive difference between the two eyes X1.00 D. Results Hyperopia (46.5%) was slightly more common than myopia (40.1%). The prevalence of myopia increased with age, whereas that of hyperopia decreased. Astigmatism was found in 66.8% of patients, and astigmatism X2 D was found in 16.8% of patients. Anisometropia was identified in 29.7% of patients, and the incidence of anisometropia correlated significantly with age as well as with astigmatism. Esotropia (22.1%) was twice as common as exotropia (10.5%). The prevalence of esotropia increased with age, but that of exotropia decreased. Fifty patients were found to have nystagmus (29.1%). Conclusions In Asian patients with Down syndrome, esotropia was more common than exotropia and hyperopia was more common than myopia. The prevalence of exotropia and astigmatism was much higher in this study than has been previously reported.

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