Alterations of auditory sensory gating in mice with noise-induced tinnitus treated with nicotine and cannabis extract
Barbara Ciralli,
Thawann Malfatti,
Thiago Z Lima
et al.
Abstract:Tinnitus is a phantom sound perception affecting both auditory and limbic structures. The mechanisms of tinnitus remain unclear and it is debatable whether tinnitus alters attention to sound and the ability to inhibit repetitive sounds, a phenomenon also known as auditory gating. Here we investigate if noise exposure interferes with auditory gating and whether natural extracts of cannabis or nicotine could improve auditory pre-attentional processing in noise-exposed mice. We used 22 male C57BL/6J mice divided … Show more
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