Alterations in the cortical thickness and the amplitude of low-frequency fluctuation in patients with post-traumatic stress disorder

Xie, Bing; Qiu, Mingguo; Ye, Zhang; Zhang, Jingna; Li, Min; Han, Chen; Zhang, Yu; Zhang, Jiajia; Wang, Jian; Chen, Wei; Du, Hanjian; Zhang, Shaoxiang

doi:10.1016/j.brainres.2012.10.048

Cited by 97 publications

(79 citation statements)

References 58 publications

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“…The findings of the current study are inconsistent with those of another resting-state study in PTSD that reported increased ALFF values in BA 10 and BA 32 [69]. The possible reason for this inconsistency is that whilst traumatized controls were recruited in the present study, the previous study included health controls.…”

Section: Discussioncontrasting

confidence: 81%

Altered spontaneous neuronal activity of visual cortex and medial anterior cingulate cortex in treatment-naïve posttraumatic stress disorder

Zhu¹,

Zhang²,

Zhan³

et al. 2014

Comprehensive Psychiatry

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Section: Discussioncontrasting

confidence: 81%

Altered spontaneous neuronal activity of visual cortex and medial anterior cingulate cortex in treatment-naïve posttraumatic stress disorder

Zhu¹,

Zhang²,

Zhan³

et al. 2014

Comprehensive Psychiatry

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“…The regional dysfunction in the two regions might arise from subtle connectivity abnormality. The thalamus and putamen had been implicated in a number of discrete, distributed corticalstriatal-thalamic circuits involved in specific cognitive functions (25). We suppose the alterations in regionally subcortical connectivity may be attributable to the high level of arousal and result in symptoms such as dissociation and flashback in PTSD (26), and the changes in subcortical regions during resting state may provide more insight into the neuronal circuitry underlying the re-experience and reawakening of traumatic events (27).…”

Section: Discussionmentioning

confidence: 98%

Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI

Zhong

Zhang

Li³

et al. 2015

Acta Radiol

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“…Similar to the procedures of previous literature (34)(35)(36)(37)(38)(39), the time series of each voxel was transformed to a frequency domain after the linear trend was removed without band-pass filtering. The square root was then calculated at each frequency of the power spectrum, and finally the sum of amplitude across 0.01-0.08 Hz was divided by that across the entire frequency range (0-0.25 Hz) to obtain fALFF.…”

Section: Methodsmentioning

confidence: 99%

Brief meditation training induces smoking reduction

Tang

Posner

2013

Proc. Natl. Acad. Sci. U.S.A.

171

119

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More than 5 million deaths a year are attributable to tobacco smoking, but attempts to help people either quit or reduce their smoking often fail, perhaps in part because the intention to quit activates brain networks related to craving. We recruited participants interested in general stress reduction and randomly assigned them to meditation training or a relaxation training control. Among smokers, 2 wk of meditation training (5 h in total) produced a significant reduction in smoking of 60%; no reduction was found in the relaxation control. Resting-state brain scans showed increased activity for the meditation group in the anterior cingulate and prefrontal cortex, brain areas related to self-control. These results suggest that brief meditation training improves self-control capacity and reduces smoking.addiction | anterior cingulate cortex | brain state | integrative body-mind training | mindfulness S moking harms nearly every organ of the body, causing many diseases and compromising smokers' health (1). Despite the negative consequences, many smokers have difficulty quitting or even reducing tobacco use (2). In addition, many teenagers are added to the smoking roll each year and may be at risk for abuse of other substances (2). Because tobacco use is often thought of as a gateway to other drug use, reducing smoking might reduce the vulnerability of youths to cocaine and other drugs (3). Although public health campaigns may have decreased the number of smokers, current methods for aiding those who persist in smoking have had limited success (4, 5). These failures may be a result of the inability to relieve withdrawal symptoms, stress, and cue-induced cravings, which often leads to drug seeking and taking (6-10). This urgent need calls for a short-term, effective intervention for reducing smoking behavior and cravings (2).One reason for addiction to tobacco may involve a deficit in selfcontrol. Self-control is important because the level of childhood self-control predicts long-term outcomes, including mental health, substance abuse, financial independence, and criminal behavior (11). Individuals at risk for substance abuse typically have deficits in self-control (12-16). Dysfunction of the prefrontal cortex (PFC), including dorsolateral PFC, anterior cingulate cortex (ACC), and medial orbitofrontal cortex, play a key role in addiction (12,17,18). In cigarette smokers, regional cerebral blood flow was reduced in the left dorsal ACC, and this correlated with a decrease in craving after smoking the first cigarette of the day (19). These reports raise the question of whether impaired self-control could be ameliorated and strengthened with intervention, and thus potentially change smoking behavior.There is emerging evidence that mindfulness meditation has the potential to ameliorate negative outcomes resulting from deficits in self-control (20-25). Although preliminary findings suggest mindfulness training shows some proof of efficacy in substance abuse, these studies are replete with limitations, including a lack of ...

show abstract

Alterations in the cortical thickness and the amplitude of low-frequency fluctuation in patients with post-traumatic stress disorder

Cited by 97 publications

References 58 publications

Altered spontaneous neuronal activity of visual cortex and medial anterior cingulate cortex in treatment-naïve posttraumatic stress disorder

Altered spontaneous neuronal activity of visual cortex and medial anterior cingulate cortex in treatment-naïve posttraumatic stress disorder

Altered cortical and subcortical local coherence in PTSD: evidence from resting-state fMRI

Brief meditation training induces smoking reduction

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