Alterations in Rat Hippocampal Glutamatergic System Properties After Prolonged Febrile Seizures
Alexandra V. Griflyuk,
Tatyana Y. Postnikova,
Sergey L. Malkin
et al.
Abstract:Febrile seizures in early childhood can lead to developmental disorders in the CNS. However, the specific mechanisms behind the impact of febrile seizures on the developing brain are not well-understood. To address this gap in knowledge, we employed a hyperthermic model of febrile seizures in 10-day-old rats and tracked their development over two months. Our objective was to determine the degree to which the properties of the hippocampal glutamatergic system are modified. We analyzed whether pyramidal glutamat… Show more
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