Alterations in lung functions based on BMI and Body fat % among obese Indian population at National Capital Region

Kamal, Ritul; Kesavachandran, Chandrasekharan Nair; Bihari, Vipin; Sathian, Brijesh; Srivastava, A. K.

doi:10.3126/nje.v5i2.12829

Cited by 8 publications

(7 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lung function impairment is associated with increased PBF in obese individuals 25 . Similar results were presented in a study of elderly subjects, demonstrating that increased PBF had a negative impact on lung function in both genders 26 .…”

Section: Discussionmentioning

confidence: 99%

Body Fat Percentage in Relation to Lung Function in Individuals with Normal Weight Obesity

Chen

Kao

Fang³

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Accumulating evidence indicates the association between obesity and lung function. However, no previous study has examined whether obesity affects lung function in normal weight participants with high body fat. We hypothesized that subjects with normal weight obesity (NWO) were inversely associated with lung function in Taiwan. The study sample was composed of participants who attended health examinations at the Tri-Service General Hospital from 2010 to 2016. A total of 7801 eligible participants who were classified as NWO were divided into quartiles by percentage body fat (PBF), which was measured by bioelectrical impedance analysis (BIA). A multivariable linear regression was performed to assess the association between PBF quartiles and pulmonary function. The relationship between PBF and the presence of obstructive and restrictive lung diseases was analyzed by a logistic regression. PBF quartiles were closely associated with reduced forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) in all adjusted models. This relationship remained significant in the male population, and a dose-dependent effect was observed. Increased PBF was associated with increased risks for the presence of restrictive lung diseases. These results presented a novel finding that body fat exhibited an inverse association with pulmonary function in NWO subjects. More comprehensive management of subjects with normal weight but high body fat, which might contribute to metabolic dysfunction and impaired pulmonary function, is needed.

show abstract

Section: Discussionmentioning

confidence: 99%

Body Fat Percentage in Relation to Lung Function in Individuals with Normal Weight Obesity

Chen

Kao

Fang³

et al. 2019

Sci Rep

View full text Add to dashboard Cite

show abstract

“…In such condition, the static lung volumes and capacities are expected to increase with weight [ 29 – 32 ]. Increased total body fat content, therefore, seems better than high BMI as an indicator of obesity as well as predictor for decreased static lung volumes and capacities [ 33 ].…”

Section: Physiological Determinant Of the Static Lung Volumes And Capmentioning

confidence: 99%

The physiological basis and clinical significance of lung volume measurements

Lutfi

2017

Multidiscip Respir Med

107

View full text Add to dashboard Cite

From a physiological standpoint, the lung volumes are either dynamic or static. Both subclasses are measured at different degrees of inspiration or expiration; however, dynamic lung volumes are characteristically dependent on the rate of air flow. The static lung volumes/capacities are further subdivided into four standard volumes (tidal, inspiratory reserve, expiratory reserve, and residual volumes) and four standard capacities (inspiratory, functional residual, vital and total lung capacities). The dynamic lung volumes are mostly derived from vital capacity. While dynamic lung volumes are essential for diagnosis and follow up of obstructive lung diseases, static lung volumes are equally important for evaluation of obstructive as well as restrictive ventilatory defects. This review intends to update the reader with the physiological basis, clinical significance and interpretative approaches of the standard static lung volumes and capacities.

show abstract

“…However, this relationship was not found for FEV1/FVC ratio. Since increased body fat decreases FVC and FEV1 31,32 , it is possible that sensitivity for respiratory function was higher for FEV1% predicted compared to FEV1/FVC ratio in the study population. Low BMI was a factor related to reduced FEV1/FVC ratio in men of all ages.…”

Section: Discussionmentioning

confidence: 96%

“…Contrastingly, high BMI was found to be a factor related to reduced FEV1% predicted in the non-elderly group. Fat accumulation in the rib cage and visceral cavity reduces respiratory function by adversely affecting functional residual capacity 14,32 . While the mean BMI for the general Japanese population is 23.7 kg/m 2 for men and 22.5 kg/m 2 for women 33 , the non-elderly group in this study had a mean BMI of 27.4 kg/m 2 .…”

Section: Discussionmentioning

confidence: 99%

Characteristics of factors for decreased lung function in elderly patients with type 2 diabetes

Ishii

Yamaguchi

Hamaya

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Chronic obstructive pulmonary disease (COPD) often accompanies type 2 diabetes mellitus (T2DM). However, background factors affecting these diseases in the elderly remain unclear. Eligible patients with T2DM were divided into two age groups—non-elderly (<65 years) and elderly (≥65 years); COPD, ratio of forced expiratory volume in one second to forced expiratory volume (FEV1/FVC ratio), and percent predicted forced expiratory volume in one second (FEV1% predicted) were examined, and factors related to reduced respiratory function according to age group were evaluated. In total, 371 patients with T2DM were analysed. COPD was found in 9 patients (5.3%) in the non-elderly group and 45 (22.5%) in the elderly group. In the elderly, male sex, low body mass index (BMI), insulin therapy, and high C-peptide immunoreactivity levels were factors related to COPD. In the non-elderly, age, female sex, high BMI were factors related to decreased FEV1% predicted. Female sex was factor related to decreased FEV1% predicted in both age groups. Low BMI was a factor related to reduced respiratory function in elderly patients and high BMI was a factor related to reduced respiratory function in non-elderly patients. Thus, BMI needs to be managed according to the age and general condition of T2DM patients.

show abstract

Alterations in lung functions based on BMI and Body fat % among obese Indian population at National Capital Region

Cited by 8 publications

References 56 publications

Body Fat Percentage in Relation to Lung Function in Individuals with Normal Weight Obesity

Body Fat Percentage in Relation to Lung Function in Individuals with Normal Weight Obesity

The physiological basis and clinical significance of lung volume measurements

Characteristics of factors for decreased lung function in elderly patients with type 2 diabetes

Contact Info

Product

Resources

About