Alterations in Gut Archaea Composition and Their Bacterial Interactions Linked to Hypertension
Wen Yuan,
Yihang Chen,
Lirong Liang
et al.
Abstract:Alterations in the gut microbiota have been linked to hypertension, with the role of archaea, despite being stable constituents, remaining largely unexplored. Shotgun metagenomic analyses of fecal samples were performed on 341 participants from 3 cohorts: discovery cohort (88 individuals), validation cohort 1 (175 individuals), and validation cohort 2 (78 individuals). Principal Coordinates Analysis (PCoA) based on Bray-Curtis distances revealed significant alterations in the composition of enteric archaea bet… Show more
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