Alteration of carotid circulation in essential hypertensive patients with left ventricular hypertrophy

Yn, Jiang; Kohara, Katsuhiko; Hiwada, Kunio

doi:10.1038/sj.jhh.1000576

Cited by 26 publications

(35 citation statements)

References 31 publications

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“…Hypertensive patients with left ventricular hypertrophy had a higher stiffness β and lower CSDC and Vd/Vs than normotensive subjects (17). We have also reported a negative correlation between Vd/Vs and the severity of asymptomatic cerebral deep gray matter lesions, "etat crible," estimated by brain MRI (29).…”

Section: Discussionmentioning

confidence: 63%

“…Ultrasound evaluation of the CCA was performed with a SONOS 5500 (PHILIPS Co., Tokyo, Japan) using a 7.5-MHz probe equipped with a Doppler system, as described previously ( 17 ). After the subjects had rested in the supine position for at least 10 min, their neck was placed in a slightly hyperextended position and then optimal bilateral visualization of the carotid artery was performed.…”

Section: Ultrasound Evaluationmentioning

confidence: 99%

“…An ultrasound imaging of the common carotid artery (CCA) has been developed for in vivo evaluation of early atherosclerotic lesions ( 14 -16 ). Hypertensive patients exhibit markedly increased intima-media thickness (IMT), a higher prevalence of plaques and increased peripheral vascular resistance in the CCA compared to normotensive individuals ( 17 ).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Relationship between Cardio-Ankle Vascular Index (CAVI) and Carotid Atherosclerosis in Patients with Essential Hypertension

et al. 2007

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Section: Discussionmentioning

confidence: 63%

Section: Ultrasound Evaluationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Relationship between Cardio-Ankle Vascular Index (CAVI) and Carotid Atherosclerosis in Patients with Essential Hypertension

et al. 2007

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“…The internal diameter of the CCA at end-diastole (Dd) and peak-systole (Ds) was determined by continuous tracing of the intimal-luminal interface of the near and far walls of the CCA in three cycles, and the results were averaged (13). The cross-sectional distensibility coefficient (CSDC) and the carotid arterial stiffness index (β) were calculated using the following formulae (12,15).…”

Section: Ultrasound Evaluationmentioning

confidence: 99%

Association between Carotid Hemodynamics and Asymptomatic White and Gray Matter Lesions in Patients with Essential Hypertension

et al. 2005

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The aim of this study was to clarify the magnitude of common carotid artery (CCA) structural and hemodynamic parameters on brain white and gray matter lesions in patients with essential hypertension (EHT). The study subjects were 49 EHT patients without a history of previous myocardial infarction, atrial fibrillation, diabetes mellitus, impaired glucose tolerance, chronic renal failure, symptomatic cerebrovascular events, or asymptomatic carotid artery stenosis. All patients underwent brain MRI and ultrasound imaging of the CCA.

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“…The same ratio also showed a significant negative correlation with PP and carotid arterial stiffness. 4 These findings suggest that hemodynamic Doppler flow patterns may reflect not only peripheral vascular resistance but also systemic arterial stiffness.…”

mentioning

confidence: 86%

Waveform of Ophthalmic Artery Doppler Flow Predicts the Severity of Systemic Atherosclerosis

Maruyoshi

Kojima

et al. 2010

Circ J

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Circulation Journal Official Journal of the Japanese Circulation Society http://www. j-circ.or.jp oronary artery disease (CAD) is a life-threatening condition that encompasses systemic atherosclerosis. Many basic-research, epidemiological, and clinical studies have been conducted with the aim of combating atherosclerotic disease. Together with aging, the progression of atherosclerosis leads to an increase in stiffening of the aorta, and in turn an increase in pulse pressure (PP) through a reduction in arterial compliance and increased pulse wave velocity. 1 Therefore, increased PP is considered as a sign of increased arterial stiffness. Elevated PP and decreased arterial compliance are also recognized as risk factors for CAD. 1,2Indices of intrarenal vascular resistance calculated from pulsed-wave Doppler velocities, such as pulsatility index (PI) and resistive index (RI), correlate positively with PP and negatively with the carotid hemodynamic pattern in patients with essential hypertension. 3 This pattern was determined by calculating the ratio of diastolic to systolic mean velocity in pulsed Doppler flow recordings of the common carotid artery. The same ratio also showed a significant negative correlation with PP and carotid arterial stiffness. 4 These findings suggest that hemodynamic Doppler flow patterns may reflect not only peripheral vascular resistance but also systemic arterial stiffness.The ophthalmic artery (OA) is the first major branch of the internal carotid artery and divides into many branches in the orbital area. Doppler imaging of the OA was recently made possible by improvements in Doppler equipment. 5 Changes in OA blood flow assessed on pulsed Doppler (OA Doppler) have provided new insights into various vascular disorders including ophthalmic diseases, carotid artery stenosis, and diabetes mellitus. 5 OA Doppler has particular anatomical advantages due to the absence of ultrasonic obstacles and the vertical angle, which differs from the parallel-signaling of carotid artery Doppler to the transducer. Such findings in the ocular fundus are associated closely with systemic atherosclerosis, with previous reports showing that atherosclerotic changes in retinal arteries are potential markers of systemic cardiovascular disease. 6,7 OA Doppler flow patterns may also reflect the severity of diabetes retinopathy. 8,9 Fukuda et al showed that the ratio of systolic to diastolic mean velocity in OA Doppler is closely involved in age and the severity of diabetic retinopathy. 10 There is little information on the relationship between OA Doppler flow and systemic atherosclerosis. We hypothesized Background: Doppler imaging of ophthalmic artery (OA), the first major branch of the internal carotid artery, provides anatomical advantages due to the vertical angle to the body surface and absence of ultrasonic obstacles. It was hypothesized that the Doppler waveform indices of OA correlate with severity of systemic atherosclerosis.

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Alteration of carotid circulation in essential hypertensive patients with left ventricular hypertrophy

Cited by 26 publications

References 31 publications

Relationship between Cardio-Ankle Vascular Index (CAVI) and Carotid Atherosclerosis in Patients with Essential Hypertension

Relationship between Cardio-Ankle Vascular Index (CAVI) and Carotid Atherosclerosis in Patients with Essential Hypertension

Association between Carotid Hemodynamics and Asymptomatic White and Gray Matter Lesions in Patients with Essential Hypertension

Waveform of Ophthalmic Artery Doppler Flow Predicts the Severity of Systemic Atherosclerosis

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