Alterações cognitivas em indivíduos brasileiros com esclerose múltipla surto-remissão

Negreiros, Marco Aurélio; Landeira-Fernández, J.; Kirchmeyer, Cíntia Villela; Paes, Renata Alves; Alvarenga, Regina Maria Papais; Mattos, Paulo

doi:10.1590/s0047-20852011000400006

Cited by 10 publications

(12 citation statements)

References 22 publications

(30 reference statements)

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“…While 45.7% of the patients with MS had deficits in episodic memory, IPS was impaired in 22.8% of patients who performed below the normative data for the PASAT (17.1%) and/or SDMT (11.4%). Similar results have been described in other Brazilian and Latin American studies: 22.5% in SDMT according to the study by Negreiros et al 38 ; 12 and 21.8%, respectively, in PASAT and SDMT, according to the study by Caceres et al 39 When analyzing verbal fluency, 42.8% of impairment was observed. Negreiros et al 38 found a similar rate of 40.7%.…”

Section: Discussionsupporting

confidence: 89%

“…Similar results have been described in other Brazilian and Latin American studies: 22.5% in SDMT according to the study by Negreiros et al 38 ; 12 and 21.8%, respectively, in PASAT and SDMT, according to the study by Caceres et al 39 When analyzing verbal fluency, 42.8% of impairment was observed. Negreiros et al 38 found a similar rate of 40.7%. In contrast, other studies reported lower indexes of around 16-19% 36,39,40 .…”

Section: Discussionsupporting

confidence: 89%

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Cognitive assessment of Brazilian patients with multiple sclerosis: weighing the impact of disability and depressive symptoms

Andrade

Cerqueira

Colodetti

et al. 2022

Dement. neuropsychol.

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Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. Cognition is not routinely assessed in patients with MS though they frequently have cognitive complaints or dysfunction. Objective: The aim of this study was to compare the cognitive status of patients with MS with age, sex, and schooling matched controls and to evaluate the potential influence of clinical parameters on cognition. Methods: A total of 35 patients with MS (mean±SD age 37.9 years±11.44, M/F: 12/23) and 33 healthy controls (mean±SD age 38.8 years±12.6, M/F: 12/21) were enrolled in this study. All subjects underwent a structured clinical assessment and the cognitive tools are as follows: Paced Auditory Serial Addition Test (PASAT), Symbol Digit Modalities Test (SDMT), Rey Auditory Verbal Learning Test (RAVLT), Digit Span, and Verbal Fluency Tests (letters F, A, and S and animal category). Psychopathology was assessed with the Mini International Neuropsychiatric Interview and the Beck Depression Inventory (BDI). The Expanded Disability Status Scale (EDSS) was used for patients. Results: Patients performed worse than controls in almost all tests, with approximately 70% of patients presenting cognitive impairment. The most affected cognitive domain was episodic memory (45.7%), followed by verbal fluency (42.8%) and information processing speed (22.8%). SDMT was inversely correlated with disease severity, as assessed by the EDSS. Depression did not influence cognitive performance in this cohort. Conclusions: Cognitive dysfunction is common among patients with MS. While motor impairment was associated with information processing speed, depression did not influence cognitive performance.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 89%

Cognitive assessment of Brazilian patients with multiple sclerosis: weighing the impact of disability and depressive symptoms

Andrade

Cerqueira

Colodetti

et al. 2022

Dement. neuropsychol.

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“…According to the symptomatology and clinical indings, there are four subtypes of MS: relapsing-remitting, secondary-progressive, primary-progressive and progressive-relapsing (8). The relapsing-remitting form is present in about 80% of cases, characterized by relapses with new or worsening of symptoms, interspersed with periods of complete or partial remission of symptoms between the relapses (9).…”

Section: Introductionmentioning

confidence: 99%

Assessment of patients with multiple sclerosis according to tests of the Multiple Sclerosis Functional Composite

2016

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“…(3,4) The demyelination refers to the destruction of myelin, a fatty materials and protein that surrounds certain nerve fibers in the brain and spinal cord, resulting in impaired transmission of nerve impulses. (5,6,7) Characterized by multiple lesions limited in size, located exclusively in the white matter of the central nervous system (CNS), with disorderly spread, responsible for clinical polymorphism.…”

Section: Introductionmentioning

confidence: 99%

Classical massage in multiplesclerosis.

Santos¹,

Laurito²,

Silva³

et al. 2015

mtprehabjournal

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Background: Multiple sclerosis is an autoimmune disease, inflammatory that affects the white matter of the central nervous system, resulting in neurological signs and symptoms that after the outbreaks, may leave sequels as the location of the lesion. Symptoms may include loss of double vision, muscle weakness, lack of balance, numbness, pain, problem in the control of the bladder and bowel, fatigue, emotional changes and intellectual impairment. Objective: To describe the effects and compromise in carrier of multiple sclerosis, to check the efficiency of classical massage in reduction of symptoms and their influence on the performance of activities of daily living. Method/Design: It is a study of controlled clinical trial with a convenience sample of individuals already framed in clinical school of physical therapy at the University Nine July (Uninove). Eight were selected individuals diagnosed with Multiple Sclerosis, between 30 and 50 years of age, without dermatological problems for the application of classical massage. The subjects were evaluated before and after the proposed intervention consists of 20 sessions of classical massage performed twice a week having a duration of 40 minutes each session. Results: In the first three months, there have been significant results demonstrated the functional assessment (MIF), but from the sixth to the twelve months remained functional stability. The quality of life (SF-36) showed that in pre-requirements of General Condition, Vitality, Social, Emotional and Mental, was increased in the first nine months and after this period, the results were not significant. In the evaluation of the balance by the scale of Berg in the first three months did not show satisfactory results, but from the third month to the sixth month there was a significant increase in the balance. The sensitivity surface showed an increase after the sixth month of application of classical massage, keeping up to twelve months proposed by the study. In profound sensitivity presented significant results from nine months of treatment. Conclusions: The present study showed that the physical therapy, through the classical massage, does not eliminate the neurological damage that attends the disease, but can act in the treatment of specific symptoms favoring the well-being and the features of patients with multiple sclerosis.

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Alterações cognitivas em indivíduos brasileiros com esclerose múltipla surto-remissão

Cited by 10 publications

References 22 publications

Cognitive assessment of Brazilian patients with multiple sclerosis: weighing the impact of disability and depressive symptoms

Cognitive assessment of Brazilian patients with multiple sclerosis: weighing the impact of disability and depressive symptoms

Assessment of patients with multiple sclerosis according to tests of the Multiple Sclerosis Functional Composite

Classical massage in multiplesclerosis.

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