“…Likewise, genes associated with intestinal, hair follicle and neural stem cells (NSCs), such hopx and alpl are strongly expressed in mantle, A/P, and amplifying cells adjacent to mantle cells, but are downregulated in central support cells, forming a ring of expression similarly to fndc7rs4 (Fig. 1O, 3G, (Li et al, 2015a;Liu et al, 2018). Genes specifically expressed in central support cells beneath the hair cells likewise express genes that label stem cells in other organs, such as fabp7/Blbp, which labels glioma stem cells, radial glia cells, NSCs, (Kim et al, 2016;Morihiro et al, 2013) and isl1 that is expressed in quiescent intestinal stem cells and stem cells in the heart (Makarev and Gorivodsky, 2014;Shin et al, 2015).…”