AlphaFind: Discover structure similarity across the entire known proteome
David Prochazka,
Terezia Slaninakova,
Jaroslav Olha
et al.
Abstract:AlphaFind is a web-based search engine that provides fast structure-based retrieval in the entire set of AlphaFold DB structures. Unlike other protein processing tools, AlphaFind is focused entirely on tertiary structure, automatically extracting the main 3D features of each protein chain and using a machine learning model to find the most similar structures. This indexing approach and the 3D feature extraction method used by AlphaFind have both demonstrated remarkable scalability to large datasets as well as … Show more
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