Alpha-mangostin, piperine and beta-sitosterol as hepatitis C antivirus (HCV): In silico and in vitro studies

In-silico Discovery of Potential Mycobacterium tuberculosis Cell Division Protein FtsZ Inhibitors: A Natural Ligand Piperine-Derived 3-Point Pharmacophore Screening and Structure-Guided Blind Docking Study

“…model serves as a powerful screening tool against a chemical database, facilitating the identification of potential lead compounds with the ability to disrupt FtsZ function. [12][13][14][15][16][17] We use structure-guided blind docking in conjunction with pharmacophore screening to decipher the dynamic interactions between the chosen ligands and the FtsZ protein. Through our computational investigation, we want to find drugs with strong interactions, advantageous binding modes, and promising inhibitory potential against M. tuberculosis FtsZ.…”